Tiziana Life Sciences (US:TLSA) Globenewswire·2025-11-13 13:30Core Viewpoint - Tiziana Life Sciences is participating in the Jefferies London Healthcare Conference to present its innovative pipeline and recent clinical milestones, particularly focusing on its lead candidate, intranasal foralumab, which targets neurodegenerative diseases [1][2][3]. Company Overview - Tiziana Life Sciences is a clinical-stage biopharmaceutical company developing breakthrough therapies using transformational drug delivery technologies, specifically intranasal foralumab, a fully human anti-CD3 monoclonal antibody [6]. Product Details - Foralumab is the only fully human anti-CD3 monoclonal antibody in clinical development, administered intranasally for conditions such as non-active secondary progressive multiple sclerosis (SPMS), Alzheimer's disease (AD), multiple system atrophy (MSA), and amyotrophic lateral sclerosis (ALS) [2][5]. - In an open-label intermediate sized Expanded Access Program, 14 patients with non-active SPMS have shown either improvement or stability of disease within 6 months [5]. Clinical Trials - Foralumab is currently being studied in a Phase 2a, randomized, double-blind, placebo-controlled, multicenter, dose-ranging trial for non-active SPMS [5]. Conference Participation - The Jefferies London Healthcare Conference will take place on November 19, 2025, where Tiziana's management will present and be available for one-on-one meetings [4].