Clearmind Medicine Announces Positive Top-Line Results from First Cohort of its FDA-Approved Phase I/IIa Clinical Trial for Alcohol Use Disorder

Core Insights - Clearmind Medicine Inc. announced positive top-line results from its Phase I/IIa clinical trial for CMND-100, a non-hallucinogenic oral drug candidate aimed at treating Alcohol Use Disorder (AUD) [1][2] - The trial demonstrated a favorable safety profile with no serious adverse events and high treatment adherence among participants, indicating the potential for CMND-100 as a breakthrough therapy for AUD [2][4] Company Overview - Clearmind is a clinical-stage biotech company focused on developing novel neuroplastogen-derived therapeutics to address under-treated health issues, particularly AUD [5] - The company holds a robust intellectual property portfolio consisting of nineteen patent families and 31 granted patents, with plans to seek additional patents as necessary [5] Clinical Trial Details - The first cohort of the trial included six patients, treated at prestigious institutions such as Johns Hopkins University and Yale University, under an FDA-approved protocol [3] - The trial is designed to assess the safety, tolerability, pharmacokinetic profile, and preliminary efficacy of CMND-100 in individuals with heavy binge drinking or AUD [3] Executive Commentary - The CEO of Clearmind expressed enthusiasm regarding the initial results, highlighting the encouraging safety profile and treatment observance, which support the company's goal of pioneering therapies for addiction [4]