Agios Pharmaceuticals(US:AGIO) Benzingaยท2025-11-19 17:58Market Overview - U.S. stocks showed mixed performance with the Dow Jones index falling approximately 0.2% while NASDAQ and S&P 500 saw slight gains of 0.19% and 0.08% respectively [1] - Communication services sector rose by 0.8%, while energy stocks declined by 1.6% [1] Company Performance - Lowe's Companies, Inc. (NYSE:LOW) shares increased over 5% after exceeding Wall Street profit expectations for Q3, reporting adjusted earnings per share of $3.06, a 5.9% year-over-year increase, surpassing the consensus estimate of $2.97 [2][3] - The company slightly missed sales expectations but raised its full-year revenue target, focusing on professional customers and online growth [2] Commodity Market - Oil prices fell by 2.4% to $59.26, while gold prices increased by 0.3% to $4,077.20 [6] - Silver and copper also saw gains, with silver up 0.2% to $50.615 and copper rising 0.4% to $4.9945 [6] Stock Volatility - WeShop Holdings Limited (NASDAQ:WSHP) shares surged 413% to $169.32 following its Nasdaq debut [8] - Freight Technologies, Inc. (NASDAQ:FRGT) shares rose 67% to $1.1045 after launching its AI-powered freight rate prediction platform [8] - Semrush Holdings, Inc. (NYSE:SEMR) shares increased by 74% to $11.79 after Adobe announced acquisition plans [8] - Agios Pharmaceuticals, Inc. (NASDAQ:AGIO) shares dropped 50% to $22.88 due to Phase 3 trial results not meeting statistical significance [8] - Carver Bancorp, Inc. (NASDAQ:CARV) shares fell 51% to $1.4702 after announcing plans to de-register its common stock [8] - Tempest Therapeutics, Inc. (NASDAQ:TPST) shares decreased by 47% to $4.94 following an acquisition announcement [8] International Markets - European shares mostly declined, with the eurozone's STOXX 600 down 0.03% and major indices like London's FTSE 100 and Germany's DAX 40 also falling [7] - Asian markets closed mixed, with Japan's Nikkei 225 and Hong Kong's Hang Seng both down, while China's Shanghai Composite and India's BSE Sensex gained [9] Economic Indicators - U.S. crude oil inventories decreased by 3.426 million barrels, significantly more than the expected 0.6 million [12] - U.S. exports rose by $0.2 billion to $280.8 billion, while imports fell by 5.1% to $340.4 billion, leading to a reduced trade deficit of $59.6 billion [12]