Humacyte Announces Presentations at VEITHsymposium Highlighting Positive Acellular Tissue Engineered Vessel (ATEV™) Clinical Results

Core Insights - Humacyte, Inc. presented significant findings on its acellular tissue engineered vessel (ATEV™) at the VEITHsymposium, highlighting its potential in vascular applications and regenerative medicine [1][2][3] Company Overview - Humacyte is a biotechnology platform company focused on developing universally implantable, bioengineered human tissues at commercial scale [1][8] - The company received FDA approval for its ATEV in December 2024 for vascular trauma indications and is conducting late-stage clinical trials for other vascular applications [8] ATEV Performance and Clinical Outcomes - ATEV demonstrated the ability to remodel into living vascular tissue, showing progressive recellularization with host cells, which is crucial for its function as a vascular graft [2][3] - In a study involving dialysis patients with Steal syndrome, ATEV showed durable patency and safety, with no graft-related infections or ruptures observed over a follow-up period of up to 35.9 months [3][4] - ATEV was reported to have superior patency and duration of use over two years compared to autogenous fistula in female patients, a subgroup with historically poor outcomes [10] Additional Research Findings - Presentations at the symposium included positive outcomes for ATEV in treating torso arterial trauma and high rates of limb salvage in trauma patients treated under humanitarian programs in Ukraine [4][10] - The ATEV's performance in complex cases suggests it could serve as a biologic alternative when autologous vein is not available, moving towards regenerative solutions in vascular surgery [4][5] Future Directions - Humacyte is exploring additional applications for ATEV, including coronary artery bypass grafts and treatment for type 1 diabetes, indicating a broadening scope of its innovative tissue engineering technology [8]