Enlivex Announces $212,000,000 Private Placement to Initiate World's First Prediction Markets Digital Asset Treasury Strategy, via RAIN token Accumulation, and the Appointment of Matteo Renzi, Former Prime Minister of Italy, to its Board

Core Insights - Enlivex Therapeutics has entered into a private investment in public equity (PIPE) agreement to sell 212 million ordinary shares at $1.00 per share, raising approximately $212 million, which will be used to implement a RAIN prediction markets token treasury strategy [3][8][9] - The company will be the first publicly-listed entity to adopt a treasury strategy centered on the RAIN token, aiming to provide investors with exposure to the rapidly growing prediction markets sector [5][9] - Enlivex continues its focus on the clinical development of Allocetra™, a novel therapy for knee osteoarthritis, a condition affecting over 32.5 million Americans [10] Company Developments - The PIPE transaction represents a premium of 11.5% from the stock's closing price on November 21, 2025 [3][8] - Matteo Renzi, former Prime Minister of Italy, will join the Enlivex Board of Directors following the closing of the private placement [2] - The closing of the transaction is expected on or before November 25, 2025, pending customary closing conditions [5] Industry Context - The prediction markets industry is experiencing significant institutional interest, highlighted by a $2 billion investment by NYSE's parent company in Polymarket and a $300 million financing round for Kalshi led by prominent venture capital firms [5] - RAIN is a decentralized predictions and options protocol built on the Arbitrum network, allowing users to create and trade custom options on various markets [4] - The protocol features a deflationary Buyback & Burn mechanism and aims to be a leading platform in the prediction markets space, similar to Uniswap in decentralized finance [4]