Stock Market Today: Nasdaq, S&P 500 Open Higher to Start Week; Novo Nordisk Plummets After Ozempic Alzheimer's Miss

Market Overview - The U.S. markets opened positively with the Nasdaq up by 1.33%, S&P 500 increasing by 0.75%, Russell 2000 rising by 0.35%, and Dow gaining 0.25% [2] Company Updates - Novo Nordisk's shares fell by 10.4% after its weight loss drug Ozempic failed to show a statistically significant reduction in Alzheimer's disease progression in a phase 3 study, negatively impacting Eli Lilly's shares, which dropped by 1% [4] - Novo Nordisk's Executive VP of Research and Development indicated that the study was pursued due to a significant unmet need in Alzheimer's, although it was considered a long-shot [5] - Inspire Medical Systems saw a significant increase in shares by 18.5% following an upgrade from Stifel, which raised the company's share target to $110 due to higher reimbursements [5] - Ingredion shares rose by 9.8% after announcing a deal to exit its stake in a joint venture with Amyris, despite facing negative news recently [5] - Centene's shares increased by 8.3% amid new analyst upgrades and optimism regarding a potential new Republican health care plan extending Obamacare subsidies for at least two years [5] Market Movers - Novocure's shares decreased by 7.3%, while New York Times Co fell by 5.5%, Paycom by 4.8%, and Popular Inc by 3.88% [6]