Nuvectis Pharma to Host a Virtual Key Opinion Leader Meeting to Discuss the NXP900 Phase 1b Program in Advanced Solid Tumors, Including the Combination with Osimertinib in NSCLC

Core Viewpoint - Nuvectis Pharma, Inc. is hosting a virtual Key Opinion Leader Meeting on December 2, 2025, to discuss the NXP900 Phase 1b Program in Advanced Solid Tumors, particularly its combination with osimertinib in non-small cell lung cancer [1][2]. Company Overview - Nuvectis Pharma, Inc. is a clinical stage biopharmaceutical company focused on developing innovative precision medicines for serious unmet medical needs in oncology [1][8]. - The lead drug candidate, NXP900, is an oral small molecule inhibitor targeting the SRC Family of Kinases (SFK), including SRC and YES1, designed to inhibit both catalytic and scaffolding functions of the SRC pathway [6][8]. NXP900 Development - NXP900 has completed a Phase 1a dose escalation study in patients with advanced solid tumors and is currently undergoing a Phase 1b single agent dose expansion study [7][8]. - A drug-drug interaction study has been completed, supporting the initiation of enrollment in the Phase 1b dose expansion combination arm, expected to begin by the end of 2025 [7]. Key Opinion Leaders - The meeting will feature Dr. Alexander Spira, Chief Scientific Officer of NEXT Oncology, and Dr. Asier Uncita-Broceta, Professor of Chemistry at the University of Edinburgh, who will discuss NXP900's development program and clinical data [2][4][5].