Regeneron (REGN) Up 20.2% Since Last Earnings Report: Can It Continue?

Core Insights - Regeneron reported Q3 2025 adjusted EPS of $11.83, exceeding the Zacks Consensus Estimate of $9.44, but down 5% from $12.46 in the previous year due to higher expenses [2] - Total revenues increased by 1% year over year to $3.7 billion, driven by higher sales of Eylea HD and Dupixent profits, surpassing the Zacks Consensus Estimate of $3.6 billion [2] Revenue Breakdown - Eylea HD generated $431 million in the U.S., up 10% year over year, exceeding the Zacks Consensus Estimate of $414 million [6] - Eylea sales in the U.S. fell 41% year over year to $681 million, missing the Zacks Consensus Estimate of $686 million, primarily due to increased competition and market share loss [4] - Total collaboration revenues reached $2 billion, an increase of 18.6% from the previous year, beating the Zacks Consensus Estimate of $1.8 billion [7] Collaboration and Product Sales - Sanofi's collaboration revenues rose 28% to $1.6 billion, driven by higher Dupixent sales, surpassing the Zacks Consensus Estimate of $1.5 billion [8] - Dupixent sales increased 27% year over year to $4.86 billion [8] - Bayer's collaboration revenues totaled $345 million, down 12% year over year [9] Cost and Margin Analysis - Gross margin on net product sales decreased to 86% from 89% due to ongoing investments in manufacturing [11] - Adjusted R&D expenses increased 18% year over year to $1.3 billion, while adjusted SG&A expenses decreased 12% to $541 million [11] Pipeline and Regulatory Updates - The FDA approved Eylea HD for various ophthalmology indications, and Regeneron plans to submit a new application for a pre-filled syringe by January 2026 [6][14] - The EMA recommended approval of Dupixent for chronic spontaneous urticaria, with a decision expected soon [13] - A phase III study of cemdisiran met its primary and secondary endpoints, with a regulatory submission planned for Q1 2026 [16] Market Performance and Outlook - Regeneron shares have increased by approximately 20.2% since the last earnings report, outperforming the S&P 500 [1] - The consensus estimate for Regeneron has shifted upward by 12.49% since the earnings release, indicating positive investor sentiment [17] - Regeneron holds a Zacks Rank 3 (Hold), suggesting an expectation of in-line returns in the coming months [20]