诺诚健华:新型TYK2抑制剂Soficitinib治疗结节性痒疹的全球II期临床试验完成首例患者给药
Zhong Zheng Wang·2025-11-28 05:24

Core Insights - Nocera Biopharma announced the completion of the first patient dosing in the global Phase II clinical trial of its novel TYK2 inhibitor Soficitinib (ICP-332) for the treatment of nodular prurigo [1][2] - Soficitinib is a highly selective oral TYK2 inhibitor developed for various T-cell related autoimmune diseases, with a strong focus on dermatological conditions such as atopic dermatitis, vitiligo, nodular prurigo, and urticaria [1] - The global market for nodular prurigo treatment is projected to grow from $2 billion in 2024 to $3 billion by 2034, with approximately 10 million patients affected worldwide [1] Company Developments - Nocera Biopharma's product pipeline covers ten autoimmune diseases, with a significant emphasis on dermatological diseases [2] - Soficitinib has demonstrated excellent efficacy and safety in Phase II clinical studies for moderate to severe atopic dermatitis, and the related research was featured in a prominent oral presentation at the American Academy of Dermatology annual meeting [2] - The company is accelerating global clinical development to provide innovative treatment solutions for more autoimmune patients [2]