Investopedia·2025-12-01 21:50Core Insights - Synopsys was the best-performing stock in the S&P 500 after announcing an expanded partnership with Nvidia, with shares jumping around 5% [6][8] - Moderna's shares fell 7% due to a report about stricter vaccine approval processes by the FDA, impacting other vaccine producers as well [3][8] - Sandisk's shares dropped nearly 6% after reversing gains from its S&P 500 debut, despite overall significant gains since its spinoff from Western Digital [4][8] - Bitcoin and major cryptocurrencies saw a decline, with Coinbase Global and Robinhood Markets shares also falling [5] - Deckers Outdoor shares rose 4.5% following an upgrade from analysts, driven by positive growth outlooks for its Hoka and Ugg brands [9] - Transport and logistics companies Old Dominion Freight Line and J.B. Hunt Transport Services saw their shares increase over 3% after positive analyst ratings [10] Company-Specific Developments - Synopsys announced a $2 billion investment from Nvidia to collaborate on AI applications, boosting its stock performance [6][8] - Moderna's revenue, primarily from its COVID-19 vaccine, is under pressure due to regulatory changes, affecting its stock negatively [3][8] - Sandisk's stock performance reflects volatility post-spinoff, despite a strong demand for AI-driven memory products [4][8] - Deckers Outdoor's stock performance is supported by strong brand demand and recent analyst upgrades [9] - Old Dominion Freight Line and J.B. Hunt Transport Services received positive analyst ratings, contributing to their stock price increases [10]