分子诊断助力肠癌早筛 《扬州市邗江区结直肠癌筛查民生工程》总结报告发布

Group 1 - The report on the colorectal cancer screening project in Yangzhou's Hanjiang District highlights the successful implementation of a non-invasive blood-based multi-gene methylation detection technology, screening approximately 200,000 residents aged 40 to 74 from 2021 to 2023, detecting 120 cases of colorectal cancer and 1,942 cases of precancerous adenomas [1] - The annual incidence of colorectal cancer in China is about 520,000 cases, with approximately 240,000 deaths, indicating a severe prevention and control situation [1] - Traditional colonoscopy is challenging for large-scale population screening due to its invasive nature, complexity, and uneven distribution of medical resources [1] Group 2 - The project has established a dual-stage screening path of "molecular initial screening + colonoscopy confirmation," which enhances screening compliance and alleviates medical resource pressure, providing a replicable and sustainable prevention model for addressing the high incidence of colorectal cancer in China [1] - The project is recognized as a "demonstration model that is feasible, sustainable, and promotable" for major chronic disease prevention in China, as stated by a Chinese Academy of Engineering academician [2] - The integration of molecular diagnostics into the colorectal cancer screening, diagnosis, treatment, and management loop is gradually being replicated in various regions across the country, with the potential to expand to other high-incidence cancers such as gastric and liver cancer, creating a larger early screening market [2]