CASI Pharmaceuticals Announces Results from CID-103 Immune Thrombocytopenia Study at the 67th American Society of Hematology (ASH) Annual Meeting

Core Insights - CASI Pharmaceuticals, Inc. is developing CID-103, an anti-CD38 monoclonal antibody aimed at treating organ transplant rejection and autoimmune diseases [1] - The company presented data from a Phase 1 open-label study of CID-103 for immune thrombocytopenia (ITP) at the 67th American Society of Hematology Annual Meeting [1] Study Details - The Phase 1 study involved adult patients with ITP and utilized a dose escalation approach with intravenous infusions of CID-103 [1] - Patients were assigned to sequential dose-escalating cohorts receiving CID-103 at doses of 30 mg (n=1), 150 mg (n=1), 300 mg (n=3), 600 mg (n=3), and 900 mg (n=3) [1] - A priming dose of CID-103 was administered prior to the cohort dose, either at 30 mg or 150 mg [1]