Bionano Recaps Advances in Optical Genome Mapping Showcased at AMP 2025

Core Insights - Bionano Genomics showcased the advancements of optical genome mapping (OGM) at the AMP Annual Meeting, emphasizing its superior ability to detect structural variants compared to traditional methods [1][4] - The conference featured thirteen studies demonstrating OGM's effectiveness in identifying clinically relevant structural variants, highlighting its potential as a high-resolution technique for understanding complex diseases [2][3] Group 1: OGM Utility and Applications - OGM has been integrated into laboratory workflows, enhancing its application in clinical and translational research settings [3] - Key studies presented included applications of OGM in recurrent pregnancy loss, pediatric low-grade gliomas, and various hematological malignancies [3] Group 2: Research Highlights - Notable presentations included the use of OGM for genome-wide structural variant detection in fresh-frozen tissue and its complementarity with next-generation sequencing in multiple myeloma [3] - The studies collectively illustrate OGM's capacity to uncover genetic mechanisms driving diseases, reinforcing its role in modern genomics [2][3] Group 3: Company Commitment - Bionano Genomics is dedicated to innovating and expanding its OGM platform, aiming to make comprehensive structural variant analysis routine and accessible [4]