Globenewswire·2025-12-16 12:30Core Insights - The healthcare and life sciences industry leaders exhibit a decline in optimism, with a 9% drop from the previous year, reflecting concerns over political and economic challenges [1][8] Political and Regulatory Challenges - Leaders are divided on the impact of President Trump's administration, with 51% viewing it positively and 49% negatively [4] - A significant 64% believe the One Big Beautiful Bill Act will increase out-of-pocket costs for patients, while 56% anticipate that the Most Favored Nation policy will disrupt supply chains [4] Artificial Intelligence Development & Usage - Despite economic challenges, 59% of respondents plan to increase their budget for AI and large-language models in 2026 [5] - AI is expected to be implemented across various functions, including internal content development (41%), internal operations (38%), and financial analysis (37%) [5] Cybersecurity Concerns - Nearly half (47%) of respondents feel their organizations are vulnerable to cyber incidents [6] - Only 60% have a crisis communications plan, a decrease from 68% in 2025, and participation in simulation exercises has dropped to 47% from 53% [6] Transactions & Capital Markets Activity - 65% of respondents expect M&A activity to rise in 2026, but only 54% are optimistic about increased IPO activity, a 7% decline from 2025 [7] - The fundraising environment is anticipated to be more challenging, with only 28% believing it will be easier to raise capital in 2026 [7]