Xin Lang Cai Jing·2025-12-19 12:48Core Insights - The National Medical Products Administration has approved the listing of a new innovative drug, Suojirolin Tablets (brand name "Xintuoan"), developed by Shanghai Shiyin Pharmaceutical Co., Ltd., for the treatment of primary hypertension, marking the ninth domestically developed innovative drug approved in Shanghai this year [1][3] Group 1: Product Details - Suojirolin is a new generation oral non-peptide small molecule renin inhibitor aimed at addressing unmet clinical needs in hypertension treatment, providing a new therapeutic option for over 300 million patients with primary hypertension in China [1][4] - Compared to traditional antihypertensive drugs, Suojirolin directly inhibits renin activity, targeting the core issues in hypertension treatment and enhancing safety through optimized molecular structure [4] Group 2: Clinical Efficacy - Clinical trial results indicate that a daily dose of 100mg Suojirolin taken for 12 weeks can safely and effectively lower blood pressure in patients with primary hypertension, providing solid evidence for a significant reduction in average sitting diastolic blood pressure [4] Group 3: Production and Commercialization - Shanghai Shiyin Pharmaceutical has designed a new production line for Suojirolin and is currently testing core equipment for tablet compression, with plans to commence commercial production by the first quarter of 2026 [2][4]