Tempus AI Approaching Profitability Despite GAAP Losses

Core Insights - Tempus AI (TEM) is showing early signs of profitability with its first positive Adjusted EBITDA in Q3 2025 and has raised its full-year revenue guidance [1][7] - The company is focusing on improving cost control and operating leverage as revenues scale, despite the Paige acquisition impacting near-term profitability [1][2] Financial Performance - Gross profit nearly doubled year-over-year in Q3 2025, driven by growth in Genomics and Data services [2][7] - Fourth-quarter 2025 Adjusted EBITDA is expected to remain positive, supported by growth trends across business segments [2] - Despite positive Adjusted EBITDA, GAAP losses continue due to stock-based compensation and other non-cash items, limiting visibility into sustainable GAAP profitability [3][7] Peer Comparison - Hims & Hers Health, Inc. (HIMS) reported robust revenue growth nearing $600 million in Q3 2025 and achieved positive net income, reflecting a transition in profitability [4] - GoodRx Holdings, Inc. (GDRX) is maintaining stable revenues while shifting towards higher-margin solutions, focusing on margin durability amid evolving growth models [5] Stock Performance - Over the past year, Tempus' shares have increased by 81.4%, significantly outperforming the industry, which declined by 2.4% [6] - TEM currently trades at a forward Price-to-Sales (P/S) ratio of 7.42X, higher than the industry average of 5.77X, indicating an expensive valuation [8]