高发季提前，本季主流毒株是它

Core Insights - The flu season in China has started earlier this year, with significant increases in flu activity since late October, leading to a surge in patient visits to fever clinics across multiple hospitals [2] - The dominant flu strain this season has shifted from H1N1 to H3N2, contributing to the severity of the outbreak due to insufficient herd immunity [2] - In Hunan province, the proportion of patients with flu-like symptoms testing positive for the flu virus has reached 60.71%, indicating a high level of flu activity [6] Group 1: Flu Activity and Impact - The flu season has commenced approximately one month earlier than in previous years, with a notable increase in hospital visits for flu-like symptoms [2] - The current dominant strain is H3N2, while H1N1 has decreased in prevalence, highlighting a shift in the flu virus landscape [2] - The high positivity rate of 60.71% among patients with flu-like symptoms suggests a significant public health concern, although it remains within the expected range compared to the past three years [6] Group 2: Public Health Response - Hunan's health authorities are actively monitoring the flu situation, utilizing sentinel hospitals and laboratory networks for real-time tracking of virus mutations and outbreak intensity [6] - Preventive measures include strict control in key locations such as schools and nursing homes, with guidelines for early detection and response to outbreaks [6] - Public health campaigns are being conducted to educate the community on recognizing early flu symptoms and effective preventive measures [6] Group 3: Healthcare System Preparedness - Hospitals in Changsha are experiencing increased patient loads, particularly in pediatrics and respiratory departments, necessitating the formation of specialized response teams [7] - The implementation of rapid testing for respiratory pathogens has been enhanced, reducing the testing time from 4-6 hours to under 2 hours, thereby improving patient care [7] Group 4: Pharmaceutical Supply and Pricing - There has been a notable increase in demand for antiviral medications such as Oseltamivir and Baloxavir, but pharmacies report stable supply and pricing due to proactive inventory management [8] - Pharmacies have initiated supply guarantees ahead of the flu season, ensuring that essential medications remain available and prices stable [8]