美股异动 | 与吉利德科学(GILD.US)达成出售实验性抗癌资产协议 Repare Ther...
Xin Lang Cai Jing·2025-12-24 14:38

Core Viewpoint - Repare Therapeutics has announced an asset purchase agreement with Gilead Sciences to acquire the experimental cancer therapy RP-3467, with a total transaction value of up to $30 million [1] Group 1: Transaction Details - The agreement includes a maximum upfront payment of $25 million from Gilead to Repare, with an additional potential payment of up to $5 million upon completion of specific technology transfer-related matters [1] - This upfront payment will impact Repare's net cash position at the time of the merger completion, increasing the cash consideration per share to approximately $2.20, up from the previously agreed $1.82 per share with XenoTherapeutics [1] Group 2: Clinical Development - Repare is advancing the POLAR Phase I clinical trial for RP-3467, assessing the safety and pharmacokinetic characteristics of the candidate drug in combination with olaparib across various tumors [1] - Olaparib is an already marketed cancer drug co-commercialized by AstraZeneca and Merck, known by the brand name Lynparza [1]