原来光污染与阿尔兹海默病风险显著相关 你知道吗

Core Viewpoint - A study published in September 2024 suggests a potential link between light pollution and an increased risk of Alzheimer's disease, providing new insights for further research in this area [1][2]. Group 1: Light Pollution and Alzheimer's Disease - The research compared light pollution levels across 48 states in the U.S. with local medical records, revealing a significant positive correlation between light pollution and Alzheimer's disease [2]. - For individuals aged 65 and older, light pollution is one of several risk factors for Alzheimer's, alongside alcohol abuse, chronic kidney disease, depression, diabetes, and hypertension [5]. - In contrast, for those under 65, light pollution may be the primary risk factor influencing the likelihood of developing Alzheimer's disease, although this only indicates a correlation, not causation [5]. Group 2: Physiological Effects of Light Pollution - A study involving 20 participants showed that those sleeping in lit rooms had faster heart rates, indicating overactivation of the sympathetic nervous system, which disrupts the body's rest during the night [8]. - Insulin secretion was also affected, with increased insulin resistance observed in participants exposed to light during sleep, potentially raising diabetes risk [10]. Group 3: Sleep Disruption and Alzheimer's Disease - Light pollution directly contributes to insomnia, with a study in South Korea indicating that 22% of 52,000 participants used sleep medications, with higher usage correlating with increased light pollution [11]. - Insomnia is closely linked to Alzheimer's disease, as a study of 511 participants found that more severe insomnia symptoms correlated with poorer cognitive performance over four years, particularly in carriers of the APOE ε4 gene [13].