创新药起飞，健康更有保障2025年十大刷屏“健闻”，“相信”正在改写我们的健康答案

Core Insights - The biopharmaceutical industry in China is experiencing a historic leap in 2025, marked by a record number of innovative drug approvals and a total foreign licensing amount exceeding $100 billion, driven by top-level policy design, industry efforts, and public confidence [1][4][30]. Group 1: Innovative Drugs - As of December 7, 2025, the number of innovative drugs approved for market in China reached 69, a significant increase from 48 in the previous year, indicating a surge in innovative research and development [4]. - The government has emphasized the importance of innovative drugs in healthcare, establishing a pricing mechanism and supporting their development [6][7]. - The approval process for clinical trials of innovative drugs has been expedited, with a new 30-day review system implemented [18][19]. Group 2: Market Transactions - In the first three quarters of 2025, the total amount of foreign licensing transactions in China's pharmaceutical sector reached $920.3 billion, with projections indicating it will surpass $1 trillion by year-end [4][30]. - A notable transaction occurred when 3SBio entered a licensing agreement with Pfizer worth $60.5 billion, highlighting the international recognition of Chinese innovative drugs [12][13]. Group 3: Clinical Advancements - Two new Alzheimer's drugs, Donanemab and Lecanemab, were rapidly approved in China, with the first prescription written in March 2025, showcasing the swift integration of innovative treatments into the market [9][10]. - China's invasive brain-machine interface has entered clinical trials, marking a significant advancement in cutting-edge medical technology [15]. Group 4: Financial Performance - BeiGene reported its first half-year profit in August 2025, indicating a turning point for leading Chinese innovative drug companies as they enter a phase of commercial viability [16][17]. Group 5: Public Health Initiatives - The HPV vaccine was included in the national immunization program, enhancing public health measures and access to preventive care for women [21][22]. - The first version of the commercial health insurance innovative drug directory was released, aiming to improve accessibility to innovative drugs through a dual-channel approach [23][24]. Group 6: Global Positioning - By October 2025, China's total foreign licensing amount for innovative drugs exceeded $100 billion, representing 49% of the global total, surpassing the United States [29][30]. - Despite being the largest supplier of active pharmaceutical ingredients, China's pharmaceutical market remains significantly smaller than that of the U.S., with local companies holding a minimal share of the innovative drug market [28][30]. Group 7: Future Outlook - The combination of policy guidance and industry efforts is expected to accelerate the transition of Chinese innovative drugs from being primarily suppliers of raw materials to becoming influential contributors in the global pharmaceutical landscape [31].