北京科研团队绘出全球首张中国“脑地图”

Core Insights - A research team in Beijing has successfully created the world's first brain map specifically for the Chinese population, establishing normal reference values for 228 core brain structures, which can significantly enhance the diagnostic accuracy for neurodegenerative diseases like Alzheimer's and Parkinson's [1][2] Group 1: Research and Development - The study was a collaboration between Beijing Tiantan Hospital and Beijing Normal University, involving 105 research centers across the country, collecting nearly 28,000 high-quality MRI data samples, including over 24,000 from healthy individuals and more than 3,900 from patients with brain diseases [1] - The findings were published in the international journal Nature Neuroscience and have entered the clinical pilot phase [1] Group 2: Clinical Application - The brain map allows for precise reflection of the developmental, mature, and aging changes in the brains of the Chinese population, addressing the limitations of using Western population data which may lead to diagnostic biases [1][2] - An individualized brain health assessment system based on this research has been piloted at Tiantan Hospital, serving over 1,000 patients, and is capable of evaluating cognitive and motor functions, predicting drug and surgical efficacy, and warning of disability progression risks [2] Group 3: Future Directions - Future plans include integrating multimodal imaging, blood biomarkers, and genetic data to develop a comprehensive multimodal brain atlas system for the Chinese population, further advancing the precision diagnosis and treatment of major brain diseases [2] - The research has been patented and partnerships with several medical imaging companies have been established for clinical applications in brain health assessment and disease diagnosis [2]