Data Featuring Haystack MRD® from Quest Diagnostics to be Presented at the 2026 ASCO Gastrointestinal Cancers Symposium

Core Insights - Quest Diagnostics announced the sharing of data on circulating tumor DNA (ctDNA) minimal residual disease (MRD) testing at the 2026 ASCO Gastrointestinal Cancers Symposium, highlighting the significance of ctDNA in colorectal cancer detection [1] Group 1: Poster Presentations - The first poster presentation focuses on the reproducibility and clinical concordance of a tumor-informed MRD assay in patients with resected colorectal cancer from the DYNAMIC Trials, led by Jeanne Tie [2] - The second presentation discusses the use of ctDNA to monitor patients undergoing total neoadjuvant treatment for locally advanced rectal adenocarcinoma, led by Eric Christenson [2] Group 2: Importance of ctDNA MRD Testing - ctDNA-based MRD testing is increasingly recognized for its ability to identify residual or recurring cancer in solid tumors, providing molecular evidence of disease recurrence months before conventional methods [3] - A recent survey indicated that 96% of oncologists believe MRD testing can identify cancer recurrence earlier than current methods [3] Group 3: About Haystack Oncology - Haystack Oncology, a subsidiary of Quest Diagnostics, has developed the Haystack MRD test, which detects ultralow levels of ctDNA with high sensitivity and specificity [4] - The test is available for commercial use as a lab-developed test and is also utilized in clinical trials as an investigational device in multiple international locations [4]