Core Insights - Carlsmed, Inc. announced a new study showing that 3D preoperative planning combined with patient-specific interbody implants significantly reduces reoperations due to mechanical complications in complex adult spinal deformity surgery [1][2]. Study Findings - The study compared 2-year revision rates between patients receiving Carlsmed's aprevo personalized interbody implants and those receiving conventional stock implants, revealing a revision rate of 4.3% (n=115) for aprevo compared to 16.6% (n=997) for stock devices, indicating a 74% relative reduction in revisions [2]. - The average 2-year revision rate due to mechanical complications across four published studies is 24.9%, making the improvement with aprevo particularly significant [3]. Clinical Implications - The combination of 3D preoperative planning and patient-specific implants aids in achieving precise alignment and reduces the risk of proximal junctional kyphosis, a serious complication in ASD surgery [3]. - The findings validate the clinical value of personalized approaches in spine surgery, enhancing patient outcomes and reducing the economic burden associated with revision procedures [3]. Technology Overview - Carlsmed's aprevo Technology Platform integrates AI-enabled preoperative planning with customized interbody implants, addressing alignment challenges and limitations of traditional stock implants [4]. Company Background - Carlsmed is a medical technology company focused on pioneering AI-enabled personalized spine surgery solutions aimed at improving healthcare outcomes and reducing costs in spine surgery [5].
Carlsmed aprevo® Lumbar 2-year Data Published in Global Spine Journal