Wayfair upgraded, Instacart initiated: Wall Street's top analyst calls

Core Insights - The article compiles significant research calls from Wall Street that are influencing market movements [1] Upgrades - Barclays upgraded Wayfair (W) to Overweight from Equal Weight with a price target of $123, increased from $104, citing accelerated market share in 2025 and expected continuation into 2026 [2] - Oppenheimer upgraded McDonald's (MCD) to Outperform from Perform with a price target of $355, reflecting a more optimistic outlook for the restaurant sector into 2026 after 2025's underperformance [2] - Barclays upgraded Lowe's (LOW) to Overweight from Equal Weight with a price target of $285, up from $259, based on a positive outlook for discretionary goods demand, particularly among mid- and high-income consumers due to upcoming tax changes [2] - Piper Sandler upgraded Hershey (HSY) to Overweight from Neutral with a price target of $213, increased from $193, noting the easing of cocoa costs and removal of cocoa tariffs, which provide Hershey with flexibility for growth and earnings enhancement [2] - BofA double upgraded Regeneron (REGN) to Buy from Underperform with a price target of $860, up from $627, driven by a more favorable view following the realization of prior underperformance concerns regarding Eylea SD and adjustments in consensus estimates [2]