多学科联手52天击退罕见肾病

Core Insights - A 7-year-old boy, referred to as Youyou, was admitted to a children's hospital due to severe symptoms including swelling and dark urine, indicating acute kidney failure [1][2] - The medical team diagnosed him with secondary IgA nephropathy and atypical hemolytic uremic syndrome (aHUS), a rare condition that can rapidly progress to kidney failure [2] Group 1: Medical Condition and Diagnosis - Initial symptoms included eyelid and leg swelling, dark urine, reduced urine output, and fatigue, leading to a diagnosis of acute kidney failure [1] - After stabilization, a kidney biopsy confirmed the presence of aHUS and IgA nephropathy, necessitating targeted treatment [2] Group 2: Treatment and Recovery - The treatment involved the use of the targeted drug Eculizumab to inhibit abnormal complement activation, along with corticosteroids and cyclophosphamide to control inflammation and protect kidney function [2] - Following 52 days of intensive care and treatment, the boy's condition improved, leading to his eventual recovery and discharge from the hospital [2] Group 3: Medical Advice - Medical professionals emphasize the importance of early diagnosis and treatment for children showing symptoms such as unexplained swelling, dark urine, and fatigue to prevent acute kidney failure and identify rare diseases [2]