Pfizer(US:PFE) The Motley Fool·2026-01-08 08:50Core Viewpoint - Pfizer's stock is facing significant challenges in 2026, with a potential for a rebound but also a likelihood of continued lackluster performance due to various factors affecting revenue and earnings [1][7]. Financial Performance - Pfizer's market capitalization stands at $144 billion, with shares currently priced at $25.28, reflecting a 6% decline over the past year [2]. - The company expects revenue for 2026 to be between $59.5 billion and $62.5 billion, which is below the $62 billion projected for 2025 [7]. - Adjusted earnings per share (EPS) for 2026 are forecasted to decline year-over-year, with the midpoint of the EPS range approximately 5.7% lower than the 2025 guidance [8]. Product Pipeline and Clinical Trials - Pfizer's acquisition of Metsera in November 2025 added promising obesity drug programs to its pipeline, with results from Phase 2b studies for MET-097i expected in early 2026 [3][4]. - Positive clinical results from MET-097i could enhance investor enthusiasm for Pfizer's position in the obesity drug market [4]. Market Conditions and Challenges - The company anticipates a revenue decline of around $1.5 billion from COVID-19 products in 2026 compared to 2025, alongside an additional $1.5 billion negative impact from products losing market exclusivity [9]. - The patent cliff for key products like Eliquis, Ibrance, and Xtandi is expected to worsen, leading to investor caution despite potential positive news from the pipeline [10]. Dividend and Long-term Outlook - Pfizer's forward dividend yield is approximately 6.8%, making it attractive for income investors even if the stock does not see significant appreciation [11]. - The company is generating sufficient free cash flow to maintain its current dividend level, with no imminent cuts expected [12]. - Management believes that new products and late-stage candidates will facilitate a return to growth in the coming years, suggesting a more optimistic long-term outlook [13].