焦点访谈 | 李博洋：细胞“打工”造万物 解码生物制造的产业潜能

Core Insights - The article discusses the emerging field of biomanufacturing, which is recognized as one of the six future industries in China's 14th Five-Year Plan, highlighting its potential to transform various sectors through innovative production methods [11][32][34]. Group 1: Definition and Process of Biomanufacturing - Biomanufacturing involves utilizing biological entities, such as microorganisms and plant or animal cells, to metabolize raw materials into desired products, effectively turning cells into small factories [5][26]. - The process includes maintaining optimal conditions for cell growth, such as temperature and pH, and providing sufficient nutrients like carbon dioxide and hydrolyzed agricultural waste [5][26]. - The production capabilities of biomanufacturing can replace traditional agricultural methods, as seen with artemisinin production, which can be synthesized in a single container rather than requiring extensive farming [32][34]. Group 2: Market Potential and Industry Growth - The biomanufacturing industry in China reached a total scale of 1.1 trillion yuan during the 14th Five-Year Plan period, indicating significant growth potential [11][32]. - China's unified large market and comprehensive manufacturing system provide a strong foundation for developing new fields such as bio-based materials and biopharmaceuticals [34]. - The integration of biomanufacturing with over two-thirds of existing industries, including traditional chemical sectors, presents opportunities for efficiency improvements and greener production methods [34]. Group 3: Technological Advancements and Innovations - Recent breakthroughs in life sciences and synthetic biology, including gene sequencing and editing technologies, are being widely applied in biomanufacturing, leading to transformative changes in production methods [9][30]. - The establishment of national key laboratories and innovation platforms has positioned China as a leader in biomanufacturing research, with over 20% of global publications and patent applications in this field [36][37]. - The development of artificial intelligence-assisted tools for synthetic biology is enhancing the efficiency of strain design and selection processes, facilitating the production of specific therapeutic compounds [34][36]. Group 4: Infrastructure and Support for Startups - The construction of pilot testing platforms is crucial for supporting biomanufacturing startups, allowing them to transition from laboratory research to large-scale production [39][41]. - Regions like Hunan are investing in infrastructure to support biomanufacturing, including a 330-acre acceleration factory set to accommodate multiple startups for large-scale production by 2026 [39][41]. - Local governments are also creating supportive regulations and funding mechanisms to foster the growth of biomanufacturing clusters, enhancing the industry's long-term viability [41]. Group 5: Future Outlook - The rapid development and market expansion of biomanufacturing in China indicate a promising future, with ongoing efforts to innovate and apply biomanufactured products across various sectors [22][43].