Humacyte(US:HUMA) Globenewswire·2026-01-08 13:00Core Insights - Humacyte, Inc. announced results from a five-year analysis of hospital charges and healthcare costs related to extremity arterial injuries, highlighting the financial burden of preventable complications [1][2][5] Group 1: Financial Impact of Complications - Average hospital charge for extremity arterial injury repair was $316,600 per patient, with preventable complications like amputation and conduit infection increasing charges by approximately $493,000 and $590,000 respectively [1][3] - The average reimbursed cost for extremity arterial injury repair was significantly lower at $75,947, indicating a disparity between hospital charges and reimbursement [3] - Vascular graft infection and amputation resulted in additional hospital charges of $589,921 and $492,986 respectively, with average reimbursements of $84,598 and $116,611 [3] Group 2: Symvess Product Overview - Humacyte's Symvess is an acellular tissue engineered vessel designed for urgent revascularization in extremity arterial injuries when autologous vein grafts are not feasible [4][6] - Symvess has demonstrated low rates of infection and high limb salvage rates compared to historical controls, with infection rates one-ninth and amputation rates one-fifth of those seen with synthetic grafts [4][5] - The product is designed to be available off-the-shelf, which can save critical surgical time in emergency situations [5] Group 3: Clinical and Market Context - The analysis included data from 964 adult patients treated for extremity arterial injuries from 2018 to 2023, prior to the FDA approval of Symvess [2] - The patient cohort had an average age of 36.5 years, with 26% treated using conduits other than autologous vein, indicating a significant market for alternative solutions like Symvess [3][5] - Recent positive results from the V005 Phase 2/3 study of Symvess provide the first long-term data for traumatic arterial repair using a biologic conduit [5]