Cai Jing Wang·2026-01-09 13:21Core Viewpoint - The announcement highlights the collaboration between the company's subsidiary, Huyou Haiyue, and AstraZeneca to conduct clinical trials for HYP-6589 in combination with Osimertinib for treating specific types of non-small cell lung cancer [1] Group 1: Company Developments - Huyou Haiyue has developed HYP-6589, a highly selective SOS1 small molecule inhibitor, which is currently in the clinical trial phase [1] - The collaboration with AstraZeneca involves a clinical trial agreement to study the safety, tolerability, pharmacokinetics, and efficacy of HYP-6589 both as a monotherapy and in combination with Osimertinib [1] Group 2: Industry Context - Osimertinib, marketed as Tagrisso, is a third-generation oral epidermal growth factor receptor tyrosine kinase inhibitor developed by AstraZeneca, already approved in China for specific non-small cell lung cancer treatments [1] - The partnership aims to explore innovative treatment options in the oncology sector, particularly for non-small cell lung cancer, which remains a significant area of focus in cancer research [1]