Tempus AI Stock Surges 82.4% in a Year: What's Driving It?

Core Insights - Tempus AI (TEM) has experienced significant growth, with shares increasing by 82.4% over the past year, outperforming the industry growth of 2.6% and the S&P 500's 19.3% increase [1][10] Company Performance - Tempus has achieved profitability on a non-GAAP basis and is focusing on disciplined expansion and long-term growth, with a portfolio that includes oncology therapy selection, hereditary testing, and minimal residual disease (MRD) [2] - The company reported a positive adjusted EBITDA of $1.5 million in the third quarter, marking a significant milestone after a decade of efforts [7] Revenue Segments - The Genomics segment has seen revenues more than double year-over-year, driven by increased oncology testing volumes and the integration of Ambry hereditary testing, with total genomics testing volumes rising by 33% [4][10] - The Data & Services segment has emerged as a high-margin revenue stream, with revenues growing by 26.1% year-over-year, primarily due to data licensing [6] Regulatory Developments - In September 2025, Tempus received FDA 510(k) clearance for its xR IVD to support drug development programs and launched a new liquid biopsy assay for treatment response monitoring [5] Market Outlook - The Zacks Consensus Estimate projects a 59.5% improvement in loss per share for 2025 and a 71.6% improvement for 2026, with revenues expected to grow by 82.3% to $1.26 billion in 2025 and reach $1.56 billion in 2026 [11]