提速百万倍！清华大学重磅成果首次实现人类基因组级靶点全覆盖筛选

Core Insights - Tsinghua University has developed an AI-driven ultra-high-throughput drug virtual screening platform called DrugCLIP, which significantly enhances the speed of new drug screening by a factor of one million, achieving full coverage of human genome targets [1][2]. Group 1: Drug Screening Technology - DrugCLIP allows for the rapid matching of small molecules to disease targets, overcoming traditional screening limitations by converting proteins and small molecules into computer-readable signals [1]. - The platform can perform 31 trillion matching calculations in a single day on a standard high-performance computer, completing the screening of 1 million candidate molecules in just 0.02 seconds [1]. Group 2: Research Achievements - Utilizing DrugCLIP, the research team has achieved full coverage screening of approximately 10,000 targets and 20,000 key sites within the human genome, analyzing over 500 million candidate small molecules and identifying more than 2 million potential effective compounds [2]. - The team has established the world's largest drug target matching database, which is available for free to global researchers [2].