Vertex(US:VRTX) ZACKS·2026-01-16 00:00Core Insights - Vertex Pharmaceuticals (VRTX) closed at $438.92, down 2.36%, underperforming the S&P 500's gain of 0.26% [1] - The upcoming earnings report is anticipated, with expected earnings of $5.05 per share, reflecting a year-over-year growth of 26.88%, and revenue projected at $3.16 billion, indicating an 8.65% increase [2] - For the full year, earnings are expected to be $18.4 per share and revenue at $11.97 billion, showing a significant earnings increase of 4280.95% while revenue remains unchanged [3] Analyst Estimates - Recent adjustments to analyst estimates for Vertex Pharmaceuticals are crucial as they reflect changes in short-term business dynamics, with positive revisions indicating confidence in performance [4] - Adjustments in estimates are linked to stock price performance, and the Zacks Rank model has been developed to leverage these changes for operational ratings [5] Zacks Rank and Valuation - The Zacks Rank system ranges from 1 (Strong Buy) to 5 (Strong Sell), with a historical average annual return of +25% for stocks rated 1 since 1988; Vertex Pharmaceuticals currently holds a Zacks Rank of 3 (Hold) [6] - Vertex Pharmaceuticals has a Forward P/E ratio of 22.52, which is higher than the industry average of 19.88, indicating a premium valuation [7] - The Medical - Biomedical and Genetics industry, to which Vertex belongs, ranks in the top 41% of all industries, suggesting strong performance potential [7][8]