Geron Corporation (GERN) Eyes Profitability in 2026 amid Restructuring Drive

Core Insights - Geron Corporation is forecasting $220–240 million in revenue from RYTELO (imetelstat) and $230–240 million in operating expenses for 2026, following a recent restructuring aimed at achieving profitability [1][2] - The company is focusing on U.S. commercialization, international expansion, and advancing its Phase 3 IMpactMF trial, with an emphasis on building clinical support for RYTELO [2][5] - A restructuring initiative is underway, which includes a workforce reduction of nearly one-third, expected to incur $18 million in restructuring charges [3][4] Financial Outlook - Geron anticipates stronger growth in the second half of 2026 as it increases outreach to physicians and patients [1] - The company has amended its loan agreement with Pharmakon Advisors, securing access to up to $125 million through July 2026 [2] Strategic Focus - The primary objectives include driving RYTELO commercial growth in the U.S., exploring international opportunities, and advancing the Phase 3 IMpactMF trial [5][6] - The restructuring is expected to significantly impact operating expenses and better position the company to meet patient needs [5]