慢性便秘勿长期用药

Core Viewpoint - The incidence of chronic constipation is rising in China, with a prevalence rate between 4% and 10%, particularly higher in women and increasing with age [1] Group 1: Patient Demographics and Impact - The number of chronic constipation patients at Tianjin People's Hospital has significantly increased due to changes in diet, lifestyle, and psychological factors [1] - Chronic constipation severely affects the quality of life, leading many patients to self-medicate or rely on long-term prescriptions, which can pose safety risks and delay diagnosis of underlying conditions [1] Group 2: Types of Laxatives - Bulk-forming Laxatives: Examples include polycarbophil and wheat cellulose; they are safe for long-term use and suitable for mild constipation, especially in pregnant women and the elderly [2] - Osmotic Laxatives: Examples include polyethylene glycol 4000 and lactulose; they soften stool and stimulate bowel movement, suitable for mild to moderate constipation [2] - Stimulant Laxatives: Examples include bisacodyl and senna; they act quickly but can lead to dependency and electrolyte imbalances if used long-term [3] - Lubricant Laxatives: Examples include glycerin suppositories and liquid paraffin; they provide rapid relief for short-term constipation [3] - Prokinetic Agents: Examples include mosapride and itopride; they enhance gut motility and are used in conjunction with other laxatives [3] - Secretagogues: Examples include linaclotide; they are prescribed for chronic constipation unresponsive to standard treatments [3] - Probiotics: Examples include various strains of Bacillus and Bifidobacterium; they help restore gut flora and improve bowel function, recommended for long-term use [3]