从“寸步难行”到重新起步 脑起搏器助力帕金森患者精准治疗

Core Viewpoint - The article highlights the successful implementation of a brain pacemaker for a Parkinson's disease patient, demonstrating significant improvements in mobility and quality of life through advanced neurostimulation technology [1][5][9]. Group 1: Patient Case Study - A 70-year-old patient, referred to as Long Laobo, experienced severe mobility issues due to Parkinson's disease for over a decade, including symptoms like freezing gait and hand tremors [3][7]. - After a comprehensive evaluation by a multidisciplinary team at Suzhou University-Suzhou Jiulong Hospital, the patient was deemed suitable for brain pacemaker surgery [3][5]. - Following the surgery on December 30, the patient showed initial improvements, and by January 29, the device was activated, leading to significant enhancements in gait and coordination [5][9]. Group 2: Technology and Treatment - The brain pacemaker used is a next-generation device capable of real-time monitoring and adjustment of stimulation parameters based on brain signals, offering a more precise approach to treatment compared to traditional methods [5][9]. - Deep brain stimulation (DBS) is recognized internationally as a surgical treatment for Parkinson's disease, involving the implantation of electrodes in specific brain regions to modulate abnormal neural circuits [7][9]. - The article emphasizes that patients who still respond to medication may benefit more from brain pacemaker therapy, highlighting the importance of thorough assessment and multidisciplinary collaboration in determining surgical suitability [9]. Group 3: Industry Context - Parkinson's disease affects approximately 5 million patients in China, presenting a significant public health challenge due to its complex symptoms, including both motor and non-motor issues [7]. - The advancements in neurostimulation technology are paving the way for improved treatment options for patients with Parkinson's disease and other neurological conditions, indicating a growing field of research and clinical application [9].