男子将降压药掰开吃导致昏迷！药师提醒：特殊剂型药品未经医嘱或明确标识，严禁掰开使用

Group 1 - A recent incident in Fujian highlighted the dangers of improperly using controlled-release medication, where a man experienced a severe drop in blood pressure after splitting a controlled-release pill, leading to a medical emergency [1] - Controlled-release tablets are designed to release medication slowly over an extended period, and breaking them can lead to rapid drug release, causing serious adverse reactions [1] - Patients should not assume that a controlled-release medication that appears intact in stool has not been absorbed, as the drug may have been released and absorbed in the body [1] Group 2 - Besides controlled-release tablets, patients should also be cautious with sustained-release and enteric-coated tablets, as improper handling can compromise their effectiveness [2] - Some sustained-release tablets can be split if they have a clear score line, but those without a score line should not be broken, as this can damage the release mechanism [2] - Enteric-coated tablets are designed to dissolve in the intestine, and breaking them can lead to premature release in the stomach, potentially causing irritation and reducing efficacy [2]