中西医结合方案逆转心肌损伤与重塑

Core Viewpoint - The project "Construction, Scientific Interpretation, and Clinical Application of the Syndrome System of Myocardial Injury and Remodeling" led by Wang Xindong's team has won the third prize of the 2025 Chinese Medicine Science and Technology Award, highlighting the potential of integrating traditional Chinese medicine with Western medicine to effectively delay or even reverse myocardial injury and remodeling [1][2]. Group 1: Clinical Application - The team has demonstrated that the integrated approach can reverse the progression of heart conditions in over 30% of patients, leading to a reduction in heart enlargement and improvement in heart function indicators [2]. - Seven patented formulas focusing on invigorating qi and promoting blood circulation have been developed and are being promoted in over 10 hospitals, benefiting thousands of patients [3]. Group 2: Research and Mechanisms - The research is supported by multiple funding sources, including nine National Natural Science Foundation projects and two Jiangsu Provincial Natural Science Foundation projects, providing a solid scientific basis for the integrated approach [2]. - The team has identified various mechanisms through which traditional Chinese medicine can intervene in myocardial cell death and regulate ion channel functions, thereby protecting heart function [2]. - A significant discovery includes the regulation of the TRPML1 gene by traditional Chinese medicine, which may offer a new direction for targeted treatment in modern medicine [2].