Vertex (VRTX) Q4 Earnings: How Key Metrics Compare to Wall Street Estimates

For the quarter ended December 2025, Vertex Pharmaceuticals (VRTX) reported revenue of $3.19 billion, up 9.6% over the same period last year. EPS came in at $5.03, compared to $3.98 in the year-ago quarter.The reported revenue compares to the Zacks Consensus Estimate of $3.17 billion, representing a surprise of +0.7%. The company delivered an EPS surprise of -0.74%, with the consensus EPS estimate being $5.07.While investors closely watch year-over-year changes in headline numbers -- revenue and earnings -- ...