植入式无创传感器研发取得重要进展

Core Viewpoint - The development of an implantable microcrystalline hydrogel sensor using near-infrared 3D printing technology represents a significant technological breakthrough in non-invasive in-situ construction for physiological signal monitoring [1][3]. Group 1: Technology Innovation - The research team has created a flexible hydrogel biosensor that can be formed directly in the body, addressing the limitations of traditional surgical implantation methods [3]. - The innovative technology utilizes near-infrared 3D printing to induce in-body photopolymerization through a core-shell upconversion nanoparticle and indocyanine green sensitization mechanism [3][4]. Group 2: Performance and Applications - In animal experiments with mice, the sensor accurately captured muscle movement states and converted them into electrical signals without any invasive procedures, demonstrating excellent monitoring capabilities [3]. - The multifunctional microcrystalline hydrogel material used in the sensor offers good flexibility and biocompatibility, paving the way for non-invasive solutions in customized manufacturing of implantable sensors [4]. - This technology has the potential for widespread application in clinical scenarios such as neuromuscular monitoring and chronic disease management, promoting the development of medical monitoring devices towards non-invasiveness, precision, and personalization [4].