Collegium Pharmaceutical touts record 2025, sees JORNAY PM driving 2026 growth at Barclays Miami Conference

Core Insights - Collegium Pharmaceutical reported a record-breaking performance in 2025, driven by the growth of its ADHD product JORNAY PM and a stable pain portfolio [5][4][21] JORNAY PM Performance - JORNAY PM achieved a remarkable growth of 48.9% year-over-year in 2025, with management highlighting its unique once-nightly dosing and efficacy upon awakening as key differentiators in the ADHD market [3][1] - The growth in 2025 was attributed to substantial volume growth of around 20% year-over-year, supported by expanded commercial initiatives and programs aligned with the back-to-school season [2][4] - For 2026, JORNAY PM is expected to generate revenue between $190 million and $200 million, reflecting approximately 31% growth at the midpoint, primarily driven by prescription demand [7][9] Pain Portfolio Insights - The pain franchise, which includes products like Nucynta, Xtampza, and Belbuca, grew by 6% year-over-year in 2025, with low- to mid-single-digit growth expected in 2026 [3][10] - The pain portfolio faces challenges from upcoming generic competition, particularly for Nucynta, which is expected to impact overall performance [11][12] Financial Performance - Collegium generated over $325 million in free cash flow in 2025 and lowered its cost of capital through refinancing, indicating strong financial health [6][19] - The company provided 2026 total revenue guidance of $805 million to $825 million, representing a 4% year-over-year increase, largely driven by JORNAY PM growth [16][7] Strategic Priorities - The company is focused on diversifying its portfolio through business development, opportunistic share repurchases, and debt reduction, with a balance sheet capacity for transactions up to approximately $1 billion [17][18] - Collegium aims to maintain a disciplined capital deployment strategy while prioritizing assets that align with its existing focus on pain management and ADHD [17][21]