Merck (MRK) Begins Phase II/II Ovarian Cancer Study on ADC Drug

Merck (MRK) announced that a phase II/III study has been initiated on its CDH6-directed DXd antibody-drug conjugate, raludotatug deruxtecan (R-DXd), in patients with platinum-resistant ovarian cancer. The first patient has been dosed in the phase II/III study called REJOICE-Ovarian01. Merck is developing R-DXd in partnership with Japan’s Daiichi Sankyo.The initiation of the REJOICE-Ovarian01 study is based on data from the ongoing phase I study in which R-DXd showed promising activity in patients with advan ...