WAYNE, Pa., Oct. 29, 2025 (GLOBE NEWSWIRE) -- Avalo Therapeutics, Inc. (Nasdaq: AVTX), a clinical stage biotechnology company fully dedicated to developing IL-1β-based treatments for immune-mediated inflammatory diseases, today announced that the Company has completed enrollment in its Phase 2 LOTUS trial of AVTX-009 in adults with hidradenitis suppurativa (HS). The LOTUS trial exceeded target enrollment of 222 patients with approximately 250 patients enrolled. Topline data from the trial is expected in mid ...

WATERTOWN, Mass., Oct. 29, 2025 (GLOBE NEWSWIRE) -- EyePoint Pharmaceuticals, Inc. (NASDAQ: EYPT), a company committed to developing and commercializing innovative therapeutics to improve the lives of patients with serious retinal diseases, today announced it will host a conference call and live webcast at 8:30 a.m. ET on Wednesday, November 5, 2025 to report its third quarter 2025 financial results and highlight recent corporate developments. To access the live conference call, please register using the au ...

Core Insights - Axogen, Inc. raised its full-year revenue guidance to at least 19% growth, equating to $222.8 million, reflecting strong market performance and operational scaling [1][8]. Financial Performance - Third quarter revenue reached $60.1 million, marking a 23.5% increase year-over-year and a 6.0% increase from the previous quarter [3][6]. - Gross margin improved to 76.6%, up from 74.9% in Q3 2024 and 74.2% in Q2 2025 [6]. - Net income for the quarter was $0.7 million, or $0.01 per share, compared to a net loss of $1.9 million, or $0.04 per share, in Q3 2024 [6][21]. - Adjusted net income was $6.1 million, or $0.12 per share, compared to $3.1 million, or $0.07 per share, in Q3 2024 [6][23]. - Adjusted EBITDA for the quarter was $9.2 million, up from $6.5 million in Q3 2024 [6][23]. Market Developments - The peripheral nerve repair market is maturing, with double-digit growth across all segments, including Extremities, Oral Maxillofacial & Head and Neck, and Breast [3][7]. - New position statements from the American Association of Hand Surgery (AAHS) and the American Society for Reconstructive Microsurgery (ASRM) recognize nerve allografts as a standard medical practice, validating the company's market development strategy [3][7]. - The total number of covered lives for nerve repair has increased to approximately 18.1 million, with coverage among commercial payers exceeding 64% [7]. Regulatory Updates - The FDA accepted the filing of the Biologics License Application (BLA) for Avance Nerve Graft, with approval anticipated by December 5, 2025 [7][8]. Future Outlook - The company expects gross margin for the year to be in the range of 73% to 75%, accounting for one-time costs related to the anticipated BLA approval [8]. - The company reiterates its expectation to be net cash flow positive for the full year [8].

Core Insights - Kirby Corporation reported net earnings of $92.5 million or $1.65 per share for Q3 2025, a 6% increase from $90.0 million or $1.55 per share in Q3 2024 [1][5] - Consolidated revenues for Q3 2025 were $871.2 million, up from $831.1 million in Q3 2024 [1] Segment Performance - **Marine Transportation**: Revenues were $484.9 million, slightly down from $486.1 million in Q3 2024. Operating income decreased to $88.6 million from $99.5 million, with an operating margin of 18.3% compared to 20.5% [3][4][6] - **Inland Marine**: Average barge utilization was in the mid-80% range, impacted by seasonal weather and softer market conditions. Spot market rates declined in the low-to-mid single digits, while term contracts remained flat [2][4][5] - **Coastal Marine**: Strong market fundamentals with barge utilization in the mid to high-90% range. Revenues increased by 13% year-over-year, and operating margins reached around 20% [6][12] - **Distribution and Services**: Revenues rose to $386.2 million from $345.1 million, with operating income increasing to $42.7 million from $30.4 million. Operating margin improved to 11.0% from 8.8% [7][9] Financial Metrics - **EBITDA**: For Q3 2025, EBITDA was $201.4 million, up from $190.5 million in Q3 2024 [11][24] - **Cash Flow**: Net cash provided by operating activities was $227.5 million, with capital expenditures of $67.2 million. Free cash flow for the quarter was $160.3 million [11][32] - **Debt and Liquidity**: Total debt stood at $1,048.9 million, with a debt-to-capitalization ratio of 23.8%. The company had $47.0 million in cash and cash equivalents [11][24] Market Outlook - **Inland Marine**: Expected to see stable market conditions with signs of improvement. Higher barge utilization is anticipated due to seasonal factors [12][15] - **Coastal Marine**: Favorable market fundamentals are expected to continue, with steady customer demand and pricing benefiting from limited vessel availability [12][13] - **Distribution and Services**: Continued strength in power generation and marine repair markets, with full-year revenues expected to rise in the mid-single digits [15][16]

Core Insights - Amarin Corporation has transitioned to a fully partnered commercialization model across all international markets, which is expected to enhance its operational efficiency and market reach [1][3] - The Q3 2025 financial results indicate a positive trend with a 17% increase in total net revenue compared to Q3 2024, driven primarily by strong U.S. sales [4][6] - The company aims to achieve sustainable positive free cash flow by 2026, reflecting confidence in its strategic actions and operational improvements [1][4] Financial Performance - Total net revenue for Q3 2025 was $49.7 million, up from $42.3 million in Q3 2024, marking a 17% increase [4][6] - Product revenue, net increased by 16% to $48.6 million, primarily due to higher U.S. sales, which rose by 34% to $40.9 million [5][7] - Operating expenses decreased by 20% to $33.3 million, largely due to a restructuring plan implemented in June 2025 [9][12] Operating Metrics - The operating loss for Q3 2025 was $11.1 million, significantly improved from a loss of $25.2 million in Q3 2024, reflecting a 56% reduction [4][14] - The net loss for Q3 2025 was $7.7 million, compared to a net loss of $25.1 million in the same quarter of the previous year, indicating a 69% improvement [15][34] - Cash and investments at the end of Q3 2025 totaled $286.6 million, down from $305.7 million in Q3 2024 [15] Strategic Initiatives - The company has established partnerships with seven parties across nearly 100 countries to leverage regional expertise and infrastructure for the commercialization of VASCEPA/VAZKEPA [3][17] - Amarin is focused on enhancing shareholder value through strategic actions and is optimistic about its global business potential [3][4]

MONTREAL, Oct. 29, 2025 (GLOBE NEWSWIRE) -- PyroGenesis Inc. (“PyroGenesis”) (TSX: PYR) (OTCQX: PYRGF) (FRA: 8PY1), the leader in ultra-high temperature processes & engineering innovation, and a plasma-based technology provider to heavy industry & defense, announces today that further to its press release dated October 1, 2025, the Company has completed the first tranche of the Second Unit Group of the previously announced non-brokered private placement (the “Private Placement”) by issuing and selling an ag ...

NOT FOR DISTRIBUTION TO U.S. NEWSWIRE SERVICES OR FOR DISSEMINATION IN THE UNITED STATES CALGARY, Alberta, Oct. 29, 2025 (GLOBE NEWSWIRE) -- Reeflex Solutions Inc. (TSXV: RFX) (“Reeflex” or the “Company”) is pleased to announce that is has continued out of the province of Ontario into the jurisdiction of the province of Alberta under the Business Corporations Act (Alberta) (the “ABCA”). Shareholders approved the continuance at the Company's Annual and Special Meeting of Shareholders held on August 29, 2025. ...

TORONTO, Oct. 29, 2025 (GLOBE NEWSWIRE) -- Electra Battery Materials Corporation (NASDAQ: ELBM; TSX-V: ELBM) (“Electra” or the “Company”) is pleased to announce the appointment of Paolo Toscano, P.Eng., as Vice President, Projects and Engineering, effective immediately. With more than three decades of experience leading large-scale mining and metals projects across North America, Mr. Toscano will oversee the construction and commissioning of North America’s first cobalt sulfate refinery in Temiskaming Shore ...

TORONTO, Oct. 29, 2025 (GLOBE NEWSWIRE) -- ThreeD Capital Inc. ("ThreeD" or the "Company") (CSE:IDK) (OTCQX:IDKFF), a Canadian-based venture capital firm focused on opportunistic investments in companies in the junior resources and disruptive technologies sectors, is pleased to congratulate HyperCycle on its recent announcement regarding the establishment of a $1.1 billion joint venture with a consortium of South Korean investors led by Addeep Inc. The joint venture aims to establish Seoul as a central hub ...

NEW YORK, Oct. 29, 2025 (GLOBE NEWSWIRE) -- eToro, the trading and investing platform, announced that it is bringing its patented CopyTrader™ technology to US users. From today, US users have the ability to instantly copy the investment strategies of real US traders across stocks, ETFs, or cryptoassets. “We are excited to bring one of eToro’s most recognized features to the world’s largest retail investing market. CopyTrader enables millions worldwide to replicate the trades of other investors and now Ameri ...