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Creative Medical Technology Holdings, Inc. Completes Enrollment in FDA-Cleared ADAPT Trial for CELZ-201-Olastrocel, Marking Major Clinical Inflection Point
Globenewswire· 2025-12-17 14:15
Core Insights - Creative Medical Technology Holdings, Inc. has successfully completed patient enrollment in its FDA-cleared ADAPT clinical trial for CELZ-201, a non-opioid therapy for chronic lower back pain [1][3][4] - The completion of enrollment marks a significant milestone, transitioning the trial into follow-up and data analysis phases, with expectations of generating meaningful clinical data [3][4][8] - CELZ-201 is positioned to address a large, underserved market, with chronic lower back pain affecting over 16 million Americans and representing a multi-billion-dollar market [3][6] Company Developments - The ADAPT trial is a randomized, double-blind, placebo-controlled study designed to evaluate the safety, tolerability, and preliminary efficacy of CELZ-201 [5] - The trial has received a positive safety review from an independent Data Safety Monitoring Board, confirming a favorable safety profile for CELZ-201 [2][5] - The company’s StemSpine® intellectual property portfolio enhances its strategic position as it moves toward later-stage clinical development and potential commercialization [7] Future Outlook - Following enrollment completion, the company plans to continue scheduled DSMB reviews, advance toward topline safety and efficacy readouts, and evaluate strategic pathways for late-stage development and commercialization [9][10] - Management emphasizes a results-driven phase, focusing on executing flawlessly and generating compelling data to unlock the full value of CELZ-201 for patients and shareholders [10]
RLTY: Misleading 9% Yield And A Case To Skip
Seeking Alpha· 2025-12-17 14:15
Core Insights - The article highlights the extensive experience of Roberts Berzins in financial management, particularly in shaping financial strategies for top-tier corporates and executing large-scale financings [1] - It emphasizes Berzins' contributions to institutionalizing the REIT framework in Latvia, aimed at enhancing the liquidity of pan-Baltic capital markets [1] - The article also notes Berzins' involvement in developing national SOE financing guidelines and frameworks to channel private capital into affordable housing [1] Group 1 - Roberts Berzins has over a decade of experience in financial management, assisting corporates with financial strategies and large-scale financings [1] - Significant efforts have been made by Berzins to institutionalize the REIT framework in Latvia, which is expected to boost liquidity in pan-Baltic capital markets [1] - Berzins is a CFA Charterholder and holds an ESG investing certificate, indicating a strong foundation in investment principles and sustainable investing [1] Group 2 - Berzins has contributed to policy-level work, including the development of national SOE financing guidelines [1] - He has worked on frameworks to channel private capital into affordable housing, addressing a critical need in the market [1] - Berzins is actively involved in thought-leadership activities to support the development of pan-Baltic capital markets [1]
Warner Bros Discovery board rejects hostile bid from Paramount
Yahoo Finance· 2025-12-17 14:15
Dec 17 (Reuters) - Warner Bros Discovery's board rejected Paramount Skydance's $108.4 billion hostile bid on Wednesday, saying it failed to provide adequate financing assurances. In a letter to shareholders, disclosed in a regulatory filing, the board wrote that Paramount had "consistently ​misled" Warner Bros shareholders that its $30-per-share cash offer was fully guaranteed, or "backstopped," by the Ellison family, led by billionaire ‌and Oracle co-founder Larry Ellison. "It does not, and never has," ...
Longeveron Granted U.S. Patent for Method of Treating Female Sexual Dysfunction Using its Proprietary Stem Cell Therapy
Globenewswire· 2025-12-17 14:15
The patent relates to methods of administering therapeutically effective amounts of isolated allogeneic mesenchymal stem cells (MSCs) to female patients with sexual dysfunction in order to increase sexual quality of lifeFemale sexual dysfunction is an extremely common unmet medical need which can have a major impact on quality of life in otherwise healthy womenLongeveron anticipates entering into licensing or partnering agreements for the potential development and commercialization of stem cell therapy for ...
SafeSpace Global Corporation (OTCID: SSGC) Appoints Harvest Communications as Investor Relations and Corporate Communications Consulting Agency
Globenewswire· 2025-12-17 14:15
Knoxville, TN, Dec. 17, 2025 (GLOBE NEWSWIRE) -- SafeSpace Global Corporation (OTCID: SSGC), an AI technology company dedicated to protecting lives across education, healthcare, transportation, and correctional environments, today announced the appointment of Harvest Communications as its new investor relations (IR) and corporate communications consulting agency. This strategic partnership underscores SafeSpace Global’s commitment to enhancing shareholder engagement and strengthening its corporate narrative ...
Jim Cramer On Lumen Technologies: Be Careful, It Has 'Run Too Much'
Benzinga· 2025-12-17 14:15
On CNBC's “Mad Money Lightning Round,” on Tuesday, Jim Cramer recommended being careful with Lumen Technologies, Inc. (NYSE:LUMN) as the stock has “run too much.”According to recent news, Lumen named Jim Fowler chief technology & product officer on Dec. 5.Cramer recommended remaining very cautious about Unusual Machines, Inc. (NYSE:UMAC) , as the company is losing significant money. “Drone technology. Highly speculative,” he added.Jones Trading, on Dec. 1, initiated coverage on Unusual Machines with a Buy r ...
Equity Market Outlook Q1 2026
Seeking Alpha· 2025-12-17 14:15
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Capstone Green Energy Selected by Leading Frozen Mexican Food Producer for C800S Microturbine Energy Solution
Businesswire· 2025-12-17 14:15
LOS ANGELES--(BUSINESS WIRE)---- $CGEH #CHP--Capstone Green Energy Holdings, Inc. (the "Company†or "Capstone†) (OTCQX: CGEH), together with its subsidiaries, a leading provider of clean technology solutions using ultra-low-emission microturbine energy systems, today announced a significant project win with a premier producer of premium frozen Mexican foods. The company, recognized for its highquality, pepperfocused product line distributed across Mexico and the United States, has selected the Capstone C80 ...
VIEW Warner Bros Discovery board rejects hostile bid from Paramount
Reuters· 2025-12-17 14:15
Warner Bros Discovery's board rejected Paramount Skydance's $108.4 billion hostile bid on Wednesday, saying it failed to provide adequate financing assurances. ...
Inspirato Announces Agreement to be Acquired by Exclusive Investments LLC
Globenewswire· 2025-12-17 14:15
DENVER, Dec. 17, 2025 (GLOBE NEWSWIRE) -- Inspirato Incorporated (“Inspirato”) (Nasdaq: ISPO), the premier luxury vacation club and property technology company, today announced that it has entered into a definitive agreement to be acquired by Exclusive Investments LLC (“Exclusive Investments”), the parent company of Exclusive Resorts. Under the terms of the agreement, Exclusive Investments will acquire all outstanding shares of Inspirato for $4.27 per share in an all-cash transaction, valuing Inspirato at a ...