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Core Insights - GXO Logistics and Greene King have achieved significant sustainability milestones through their partnership, focusing on fleet decarbonisation, waste reduction, and community impact [1][2] Decarbonisation Efforts - Since 2019, GXO and Greene King have successfully reduced carbon intensity (gCO2e/km) through technology and behavioral changes, including trials of biodiesel, HVO, and electric vehicles, which can reduce emissions by up to 90% compared to diesel [3] Waste Reduction and Recycling - The partnership has effectively utilized GXO's reverse logistics capabilities, resulting in the elimination of over 160,000 journeys annually and recycling over 16,000 tonnes of waste in 2024 [1][4] - In 2024, Greene King expanded its recycling initiatives to include ink cartridges, batteries, correx boards, and crushed glass in London [4] Community Support - Over 90% of excess food at depots was donated to charities, leading to an estimated 240,000 meals donated in 2024 [5] - The Tub2Pub campaign collected over 240,000 confectionery tubs, raising more than £10,000 for Macmillan Cancer Support, with recycled plastic repurposed into furniture [8] Operational Efficiency - A structured driver performance management system improved fuel efficiency (MPG) by over 10% in 2024, while investments in Eco Drive hydro-electric refrigeration technology reduced fuel use by 2-4% since 2022 [6] - Energy consumption during deliveries was cut by up to 50% through the installation of strip and air curtains in refrigerated trailers [6] Material Recycling - The partnership has recycled significant quantities of materials, including over 2.7 million litres of used cooking oil, more than 4,000 tonnes of cardboard, 250+ tonnes of metal, 55+ tonnes of plastic, and 9,000+ tonnes of food waste sent to anaerobic digestion [7]

Core Insights - Arcutis Biotherapeutics is presenting new data on ZORYVE (roflumilast) efficacy for seborrheic dermatitis, atopic dermatitis, and psoriasis at the EADV Congress in Paris from September 17-20, 2025 [1] Efficacy of ZORYVE - ZORYVE foam 0.3% shows significant improvement in seborrheic dermatitis, with an Investigator Global Assessment (IGA) Success rate of 79.5% compared to 58.0% for the vehicle at Week 8 [5] - The treatment is effective across diverse populations, with similar efficacy observed among different races and ethnicities [5] - ZORYVE cream 0.05% demonstrates improved quality of life and reduced family impact in children aged 2-5 years with atopic dermatitis [4][6] - Both ZORYVE cream 0.3% and foam 0.3% improve signs and symptoms of plaque psoriasis in individuals with facial and/or genital involvement [7] Safety and Tolerability - ZORYVE foam 0.3% is well tolerated, with improvements in hypopigmentation and hyperpigmentation observed across all subgroups [5] - The treatment has shown minimal irritation at the application site in children, indicating good tolerability [6] Product Information - ZORYVE is the leading prescribed topical therapy for atopic dermatitis, seborrheic dermatitis, and plaque psoriasis [10] - The product is a selective phosphodiesterase-4 (PDE4) inhibitor, targeting inflammatory mediators [10] - ZORYVE cream 0.3% and foam 0.3% are FDA-approved for various age groups, with specific indications for plaque psoriasis and seborrheic dermatitis [11][12][13] Company Commitment - Arcutis Biotherapeutics emphasizes its commitment to advancing innovative therapies for inflammatory skin diseases, aiming to improve patient lives [9][17]

The valuation is based on recent transaction benchmarks and central rights rather than the sum of individual team values. “With the tenth team onboard, the league is now valued at close to Rs 500 crore,” said Tuhin Mishra, co-founder of PVL and Baseline Ventures. “Teams are valued between Rs 50–70 crore depending on performance and sponsorships.”Mishra said earlier projections of $90 million were “aspirational,” while actual deals were “closer to Rs 400–500 crore.” “Valuations were around Rs 400 crore when ...

Core Insights - The article emphasizes three companies—Waste Management, Intuitive Surgical, and Marriott International—as strong candidates for long-term investment due to their competitive advantages and stable cash flows [2][3]. Waste Management - Waste Management (WM) reported second-quarter revenue of approximately $6.4 billion, reflecting a 19% year-over-year increase, driven by solid performance in core operations and contributions from a healthcare disposal acquisition [5]. - The legacy disposal business saw a revenue increase of 7.1% year over year, indicating robust growth even without acquisitions [5]. - WM's management projects full-year free cash flow between $2.8 billion and $2.9 billion, significantly up from an initial guidance of $125 million, supporting dividends and buybacks while allowing for growth investments [6]. - The company's scale, route density, and long-term contracts create a competitive moat that is difficult for new entrants to penetrate [6]. Intuitive Surgical - Intuitive Surgical reported second-quarter revenue of about $2.44 billion, a 21% year-over-year increase, driven by higher placements of da Vinci systems and increased procedure volumes [9]. - The installed base of da Vinci systems grew at a double-digit rate, and management expects procedure growth of approximately 15.5% to 17% in 2025 [9][10]. - The company has a strong balance sheet with significant cash reserves and no debt, enhancing its resilience [12]. - Intuitive Surgical's price-to-earnings ratio is around 61, indicating that much of the potential upside is already reflected in the stock price [11]. Marriott International - Marriott International's second-quarter revenue per available room (RevPAR) increased by 1.5% year over year, with international markets growing by 5.3% [13]. - Non-GAAP earnings per share rose to $2.65, up from $2.50 in the previous year, and adjusted EBITDA reached approximately $1.4 billion, a 7% increase year over year [13]. - The company repurchased about $0.7 billion of stock during the quarter and has returned approximately $2.1 billion year to date through dividends and buybacks [13]. - Marriott's asset-light model, focusing on franchising and management rather than ownership, allows for low capital needs and strong cash conversion [14].

RWA crypto is set for a massive shakeup this holiday season, with Bitwise filing for a groundbreaking Stablecoin and Tokenization ETF. If approved, the fund is expected to launch just before Thanksgiving, potentially triggering a year-end FOMO rally for stablecoin and real-world asset-linked tokens. With the stablecoin market now at $290Bn and tokenized assets climbing to $66Bn, this ETF could be the spark that brings institutional capital flooding into crypto. Here’s why this development matters and how ...

The Ether Machine, an Ethereum-focused treasury management firm, has filed a draft registration statement with the US Securities and Exchange Commission (SEC) as it moves forward with plans to go public through a merger. Key Takeaways: The Ether Machine has filed an SEC Form S-4 to go public via a SPAC merger with Dynamix Corporation. The firm has amassed 495,362 ETH, valued at over $2.1 billion, making it the third-largest corporate Ethereum holder. Founder Andrew Keys contributed nearly $741 millio ...

Core Viewpoint - The Federal Reserve is anticipated to cut interest rates due to internal disagreements over policy direction and an ongoing leadership transition [1] Group 1: Interest Rate Policy - The Fed's potential interest rate cut is influenced by differing opinions among policymakers regarding the current economic conditions and future outlook [1] - The leadership transition within the Fed is contributing to uncertainty in policy decisions, which may lead to a more accommodative monetary stance [1] Group 2: Economic Implications - A reduction in interest rates could stimulate economic growth by making borrowing cheaper for consumers and businesses [1] - The anticipated rate cut reflects concerns about economic slowdown and inflationary pressures, which may necessitate a shift in monetary policy [1]

With a market cap of $29.3 billion, Broadridge Financial Solutions, Inc. (BR) is a global financial technology leader that provides investor communications and technology-driven solutions to banks, broker-dealers, asset managers, corporate issuers, and other financial institutions. Broadridge plays a critical role in enhancing transparency, efficiency, and engagement across the financial services industry. Companies valued at $10 billion or more are generally classified as “large-cap” stocks, and Broadrid ...

Core Insights - The excitement surrounding forward stock splits in high-profile companies has significantly contributed to the S&P 500's performance in 2025, alongside the trend of artificial intelligence [1][2] Group 1: Stock Split Dynamics - A stock split allows companies to adjust their share price and outstanding share count without affecting market capitalization or operating performance [2] - Investors typically favor companies that announce forward splits, as these are perceived to make shares more affordable for retail investors [4] - Companies completing forward splits often demonstrate superior innovation and execution compared to their competitors [4] Group 2: Company Performances - O'Reilly Automotive has seen a 36% year-to-date increase, driven by a 15-for-1 forward split and strong demand for auto parts due to the aging vehicle population [5][6][7] - Fastenal's shares are up 32% year-to-date, benefiting from its corporate culture of frequent stock splits and strong ties to contract sales, which account for over 73% of its net revenue [11][14] - Interactive Brokers Group has outperformed with a 44% year-to-date increase, supported by a favorable stock market environment and significant investments in technology that enhance customer offerings [17][18][19][20]