Core Insights - The company is optimistic about biological development in Q2 2025, which is expected to lead to increased volume and positive cost development in the latter half of the year [1] - The merger with Wilsgård AS enhances SalMar's presence in Norway and strengthens its operational capabilities [2][3] - SalMar has issued NOK 2 billion in new green bonds to support sustainable development and improve capital access [3] - The company has increased its volume guidance for 2025, anticipating a total harvest of 298,000 tonnes, an 18% increase compared to 2024 [5] - Despite lower salmon prices in the first half of 2025, strong demand for SalMar's products continues, with expectations of lower global supply growth in the second half [6] Financial Performance - Q2 2025 operational EBIT for Norway was NOK 696 million, with a harvest volume of 54,500 tonnes and EBIT per kg of NOK 12.8 [8] - Group operational EBIT for Q2 2025 was NOK 524 million, with a total harvest volume of 64,500 tonnes and EBIT per kg of NOK 8.1 [8] - The first half of 2025 was characterized by lower salmon prices due to increased volume and a high proportion of downgraded fish [8] Operational Developments - Strong biological performance was noted in Northern Norway, contributing to positive cost development [8] - The company is entering the third quarter with record-high biomass for the season, setting the stage for increased volume [4] - The share of superior quality fish has significantly increased from July 2025 onwards compared to the first half [4]

Core Points - Invivyd, Inc. announced a public offering of 74,811,404 shares of common stock at $0.52 per share, along with pre-funded warrants for 21,342,442 shares at $0.5199 each, aiming for gross proceeds of approximately $50 million [1][3] - The offering is expected to close on or about August 22, 2025, subject to customary closing conditions [1] - Cantor is acting as the sole book-running manager for the offering [2] Use of Proceeds - The net proceeds will be utilized for trial protocol development and advancement of the VYD2311 clinical program, research and development for pipeline programs including RSV and measles, and efforts related to monoclonal antibody therapy for Long COVID and COVID-19 Post-Vaccination Syndrome [3] Company Overview - Invivyd, Inc. is a biopharmaceutical company focused on protection against serious viral infectious diseases, starting with SARS-CoV-2, and has a proprietary technology platform for developing antibodies [7]

Core Insights - A groundbreaking achievement in treating Type 1 diabetes mellitus (T1DM) has been reported by Professor An Chiying and her team at Shenzhen Hengsheng Hospital, where 24 patients have successfully discontinued insulin therapy through holistic integrative medicine (HIM) since June 2024, with the longest insulin-free duration reaching 14 months [1][5] Group 1: Treatment Methodology - The HIM model combines traditional Chinese medicine (TCM), orthomolecular medicine, functional medicine, and lifestyle medicine, focusing on immune blockade and metabolic balance, alongside precision remote digital healthcare to restore islet function [2][3] - The treatment protocol involves multidisciplinary collaboration, including precision diagnostics, immune regulation through molecular nutrition and TCM, metabolic repair via acupuncture and herbal medicine, and precision monitoring using artificial intelligence for personalized treatment adjustments [3] Group 2: Clinical Outcomes - Over a two-year observation period, 70 T1DM patients were treated, with 24 patients (34%) completely discontinuing insulin use while maintaining stable blood glucose levels (HbA1c < 7%) and showing significant recovery of islet function as indicated by C-peptide testing [5][6] - Patients diagnosed early with T1DM and having a C-peptide level above 0.5 ng/ml can stop insulin, while those with lower islet function can significantly reduce insulin dosage once blood glucose levels are stabilized [6] Group 3: Expert Evaluation and Implications - Academician Fan Daiming of the Chinese Academy of Engineering praised the results, stating that they challenge the traditional view of lifelong medication for T1DM and highlight the potential of HIM as a new clinical treatment paradigm [7] - The global T1DM patient population is approximately 9 million, with traditional treatment costs exceeding RMB 10,000 annually, indicating that HIM could alleviate both financial and health burdens on patients [7]

Group Performance - Telix Pharmaceuticals reported a revenue of $390.4 million for H1 2025, representing a 63% increase compared to H1 2024's $239.6 million [5][8] - The group gross profit margin was 53%, reflecting a change in product mix to include third-party RLS sales, while the Illuccix® margin remained stable [5] - Adjusted EBITDA was $21.1 million, down from $37.1 million in H1 2024, attributed to increased operating expenditures from strategic acquisitions and investments [5][8] Precision Medicine Segment - Revenue from the Precision Medicine segment increased by 30% compared to H1 2024, driven by higher Illuccix dose volumes [5] - Illuccix gross margin remained stable at 64% [5] - Selling and marketing expenses rose to $40.9 million due to investments in commercial infrastructure for new product launches [5] Manufacturing Solutions - Telix Manufacturing Solutions (TMS) reported $109.5 million in revenue, with $79.0 million from third-party PET and SPECT product sales [5] - Operating expenses for TMS were $30.5 million, which included $14.9 million for the RLS business and $15.6 million for start-up and integration activities [5] - TMS facilities are located in the U.S., Belgium, Australia, and Japan, enhancing global production capabilities [5] Research and Development - Total R&D investment was $81.6 million, a 47% increase year-over-year, with 54% allocated to the therapeutics pipeline [5] - Key milestones included the completion of target enrollment for Phase 3 studies and approvals for new therapeutic studies [5][6] - Full year R&D investment guidance is maintained, expecting a year-over-year increase of 20% to 25% compared to FY 2024 [10] Financial Guidance - The company confirmed FY 2025 revenue guidance of $770 million to $800 million, reflecting expected contributions from Illuccix sales and RLS [10] - Positive operating net cash flow of $17.7 million was reported, with a cash balance of $207.2 million following significant M&A investments [5]

Core Insights - Ascentage Pharma reported strong business momentum in the first half of 2025, with a 93% year-over-year growth in Olverembatinib sales to $30.3 million, driven by expanded NRDL coverage in China [2][6][7] - The approval of Lisaftoclax in July 2025 marks a significant milestone as the first Bcl-2 inhibitor approved for CLL/SLL treatment in China, with commercial sales commencing shortly after [2][13] - The company has a robust pipeline with nine registrational clinical trials ongoing, including three cleared by the FDA, demonstrating its commitment to innovative cancer therapies [2][3] Financial Performance - Total revenue for the six months ended June 30, 2025, was $32.6 million, a decrease of 71.6% compared to $113.4 million in the same period of 2024, primarily due to the absence of intellectual property revenue recorded in 2024 [12] - Product sales of Olverembatinib increased by 92.5% on a constant currency basis, contributing significantly to the overall revenue [12] - The company reported a loss of $82.5 million for the first half of 2025, compared to a profit of $22.4 million in the same period of 2024, with a loss per share of $0.24 [19] Commercial and Clinical Developments - Olverembatinib is the first third-generation BCR-ABL1 TKI approved in China for CML treatment, with ongoing evaluations for additional indications [3][28] - Lisaftoclax is being evaluated in multiple registrational Phase III trials for various hematologic malignancies, including CLL/SLL and AML [9][29] - The company completed a financing round in July 2025, raising $190.1 million in net proceeds, enhancing its financial position to support commercialization and development efforts [2][21] Operational Metrics - The number of pharmacies and hospitals where Olverembatinib is available increased by 17% to 782, with a notable 47% increase in hospitals to 295 as of June 30, 2025 [7] - Selling and distribution expenses rose by 53.7% to $19.2 million, reflecting increased commercialization efforts for Olverembatinib and preparations for Lisaftoclax [14] - Research and development expenses increased by 19.0% to $73.8 million, driven by ongoing global clinical trials [15]

Core Viewpoint - Perseus Mining Limited has updated its estimates of Mineral Resources and Ore Reserves as of June 30, 2025, reporting significant increases in both categories, indicating growth in the company's gold assets [1][2]. Mineral Resources Summary - The total Measured and Indicated (M&I) Mineral Resources are now estimated at 7.8 million ounces (Moz) of gold, with a total of 185.9 million tonnes (Mt) grading 1.30 grams per tonne (g/t) [2][10]. - This represents an increase from the previous year's estimate of 4.9 Moz of gold from 115.9 Mt grading 1.31 g/t [10]. - Inferred Resources are reported at 39.9 Mt grading 1.5 g/t for 1.9 Moz of gold, up from 1.3 Moz from 24.1 Mt grading 1.6 g/t in the prior year [10]. Ore Reserves Summary - The Proved and Probable Ore Reserves total 5.0 Moz of gold, with 116.7 Mt at an average grade of 1.33 g/t [2][6]. - This marks an increase of 2.1 Moz in Ore Reserves compared to the previous year, reflecting the company's strategic reassessment of growth opportunities within its portfolio [3][6]. - The breakdown of Ore Reserves includes 20.9 Mt of Proved Reserves and 95.8 Mt of Probable Reserves [6]. Project-Specific Details - The Edikan Gold Mine contributes significantly to the estimates, with 29.7 Mt of total Ore Reserves at a grade of 1.03 g/t, equating to 980,000 ounces [6]. - The Sissingué Gold Mine and Yaouré Gold Mine also contribute notable amounts, with respective total Ore Reserves of 3.7 Moz and 1.4 Moz [6]. - The Meyas Sand Gold Project (formerly Block 14) includes Indicated Mineral Resources of 3.3 Moz and a Probable Mineral Reserve of 2.9 Moz, which are not included in the main estimates [2][11]. Strategic Insights - The company is focusing on optimizing its portfolio rather than adhering to fixed investment targets for each asset, aiming to balance growth investments with cash margins [3]. - The updated estimates are in accordance with the JORC Code (2012) and reflect a commitment to maintaining high standards in reporting mineral resources and reserves [12][19].

Company Overview - Elite Express Holding Inc. (ETS) is a Delaware holding company that operates through its wholly owned subsidiary, JAR Transportation Inc., based in California [5] - ETS specializes in last-mile delivery services, focusing on transporting packages from distribution centers to end customers within defined service areas [5] - The company utilizes logistics software to enhance operational efficiency, route planning, driver oversight, and regulatory compliance [5] Initial Public Offering (IPO) Details - ETS announced the pricing of its initial public offering of 3,800,000 shares of Class A common stock at a public offering price of $4.00 per share, resulting in gross proceeds of approximately $15.2 million before deducting underwriting discounts and offering expenses [1] - The underwriters have a 45-day option to purchase up to an additional 570,000 shares of Class A common stock at the initial public offering price [1] - The shares are expected to begin trading on the Nasdaq Capital Market under the ticker symbol "ETS" on August 21, 2025, with the offering expected to close on August 22, 2025, subject to customary closing conditions [2] Regulatory and Compliance Information - A registration statement on Form S-1 was filed with the U.S. Securities and Exchange Commission (SEC) and was declared effective on August 20, 2025 [3] - The offering is being made only by means of a prospectus forming part of the effective registration statement, with copies of the final prospectus to be available on the SEC's website [3]

Core Viewpoint - Currency Exchange International, Corp. ("CXI") has announced an amendment to its normal course issuer bid (NCIB), increasing the maximum number of common shares that may be repurchased from 316,646 to 377,000, which represents 10% of the public float as of the current date [1][5]. Group 1: Share Buyback Program - The amendment to the NCIB is effective from August 25, 2025, and allows for the repurchase of an additional 60,354 shares [1]. - As of August 18, 2025, CXI has repurchased 221,400 common shares at a weighted-average price of C$20.84 since the program began on December 2, 2024 [2]. - The company will purchase shares on the open market through the TSX and alternative Canadian trading platforms, with all repurchased shares being cancelled [3]. Group 2: Purchase Guidelines - Under TSX policies, CXI can repurchase a maximum of 1,000 shares in a single trading day and is allowed to make a block purchase once per week [4]. - The purchases will be funded through available cash, and the actual number and timing of purchases will be determined by CXI [4]. Group 3: Rationale for Buyback - The Board of Directors believes that the market price of the common shares may not fully reflect their long-term value, making the buyback an attractive use of available funds [5]. - The company has amended its automatic share purchase plan (ASPP) to allow for the purchase of up to 377,000 shares under the ASPP, which will be included in the NCIB calculations [6]. Group 4: Company Overview - Currency Exchange International provides foreign exchange technology and processing services for banks, credit unions, businesses, and consumers, with primary products including currency exchange, wire transfer payments, and foreign cheque clearing [7].

Core Viewpoint - NOVAGOLD and Paulson Advisers LLC are advancing the Donlin Gold project in Alaska, focusing on stakeholder engagement and preparing for a Bankable Feasibility Study (BFS) amid a favorable gold market [1][2][3]. Group 1: Project Development and Stakeholder Engagement - A project workshop was held in July 2025 in Alaska, involving key stakeholders and representatives from NOVAGOLD and Paulson, aimed at advancing the Donlin Gold project [1]. - Meetings with local stakeholders, including Calista Corporation and The Kuskokwim Corporation (TKC), emphasized collaboration and the project's commitment to responsible development [2][3]. - The project is expected to produce over one million ounces of gold annually over a 27-year mine life, highlighting its significance as one of the largest gold mines in the U.S. [13]. Group 2: Strategic Planning and Infrastructure - A contract has been awarded to prepare the Request for Proposals (RFP) for the updated BFS, with top-tier engineering firms expected to be selected by Q4 2025 [3][11]. - Discussions with natural gas pipeline developers are ongoing to explore options for delivering natural gas to Southcentral Alaska, which could benefit the Donlin Gold project [10]. - The 2025 drill program has been completed, focusing on converting and expanding reserves, with an additional 3,000 meters approved for geotechnical drilling [12][17]. Group 3: Company Overview and Financial Position - NOVAGOLD is well-financed and focuses on developing the Donlin Gold project, which has approximately 39 million ounces of gold in the Measured and Indicated Mineral Resource categories [13][17]. - The project is regarded as one of the largest and highest-grade open-pit gold deposits globally, with significant potential for future production [13].

Core Viewpoint - Canadian North Resources Inc. reported significant advancements in its bio-leaching tests aimed at enhancing the recovery of nickel, cobalt, copper, and PGE from the Ferguson Lake Project, indicating a potential for a low-cost, low-carbon mining operation [2][3][4]. Operational Highlights - The company expanded its bio-metallurgical programs, achieving nickel extraction rates of 97.86-98.5% and cobalt extraction rates of 96.9-97.7%, with ongoing efforts to achieve high recoveries of copper and PGE [4][5]. - The company is actively engaging with local governments and Indigenous communities to secure necessary permissions and permits for environmental baseline studies [5][6]. Financial Performance - For the quarter ended June 30, 2025, the company reported cash and cash equivalents of $143,233 and a net loss of $292,890, equating to $0.00 per share [7]. Project Development - The Ferguson Lake Project is recognized as one of the largest and highest-grade copper-nickel-cobalt-PGE deposits in North America, with a substantial mineral resource estimate [6][10]. - The project contains Indicated Mineral Resources of 66.1 million tonnes, including 1,093 million pounds of copper, 678 million pounds of nickel, and 79.3 million pounds of cobalt, among other valuable metals [10]. Strategic Initiatives - The company has initiated a Normal Course Issuer Bid, repurchasing 202,300 common shares at an average price of $0.98 per share, reflecting management's commitment to enhancing shareholder value [6][11].