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合成生物学行业深度:驱动因素、前景展望、产业链及相关公司深度梳理
慧博投研·2024-05-12 16:00

Industry Overview - Synthetic biology is an emerging discipline that combines biology, chemistry, medicine, agriculture, engineering, computer science, and data science to design and create artificial life systems, with the potential to disrupt existing industries [3] - The field has evolved through four stages: creation (2000-2003), expansion and development (2004-2007), innovation and application transformation (2008-2013), and a new development phase (2014-present) [8][9][11][12] - Synthetic biology has three major strategic and commercial significances: replacing traditional fossil-based raw materials, developing new synthetic routes using local biomass, and disrupting global product supply chains [13][14] Technology Pathways - Synthetic biology can be divided into "cell-based synthetic biology" and "cell-free synthetic biology," with the key difference being the presence of a cell membrane system [15] - Cell-based synthetic biology focuses on assembling biosynthetic pathways within cells, utilizing microbial cell factories (MCFs) for target product synthesis [17] - Cell-free synthetic biology allows for greater design freedom by enabling gene transcription and protein translation outside of living cells, maximizing biosynthetic efficiency [20] Market Potential - The global synthetic biology market is projected to grow at a CAGR of 20%-30%, reaching hundreds of billions of dollars in the coming years [56][57] - The healthcare sector dominates the market, accounting for 39.65% of the total market in 2019, with a projected CAGR of 18.95% from 2019 to 2024 [58] - The food and agriculture sectors are expected to experience rapid growth, with CAGRs of 64.61% and 64.21%, respectively, from 2019 to 2024 [58] Key Companies - Huabang Biotechnology: A leading platform-based synthetic biology company with expertise in fermentation and enzymatic production of amino acids, vitamins, and bio-based materials [72][73][74] - Chuanning Biotechnology: A major player in antibiotic intermediates, leveraging advanced fermentation technologies and large-scale production capabilities [80][81][82] Challenges and Opportunities - The industry faces challenges in mass production, product selection, and technological versatility, as evidenced by the struggles of industry giants like Amyris and Zymergen [67][68][69][70] - China has the potential to leapfrog in synthetic biology due to its strong engineering talent and industrial capabilities, representing the future of the industry [71]