多点突破，盘点9大类高端生命科学仪器国产替代进程

Core Viewpoint - The article highlights the emergence of domestic high-end life science instruments in China, driven by government support for technological innovation and the efforts of local researchers, marking the beginning of a "domestic substitution" trend in the market [2][5]. Group 1: Market Overview - In recent years, the market for high-end life science instruments has been dominated by foreign companies, with prices often exceeding millions, creating significant pressure on research funding and hindering the development of life science research in China [4]. - The recent bidding results from a major project by the Ministry of Education show that domestic instruments accounted for less than 20% of the total, with only four million-level domestic instruments selected, including products from Ai Rui Technology and Su Yuan Gene [3][4]. Group 2: Key Instrument Categories - Gene Sequencing Instruments: The market has seen a significant shift with domestic brands gaining ground, particularly after the ban on certain foreign products. Domestic brands like BGI have increased their market share, with high-throughput sequencing instruments typically priced over one million [6]. - High-End Optical Microscopes: Domestic companies have made notable advancements in various types of high-end optical microscopes, achieving varying degrees of domestic substitution in categories such as super-resolution and confocal microscopes [7][8]. - Electron Microscopes: The domestic market for scanning electron microscopes, previously dominated by foreign brands, is now seeing the emergence of local companies like Guoyi Quantum and Zhongke Keyi, with significant breakthroughs in technology and product offerings [14]. - Flow Cytometers: The domestic flow cytometer market is rapidly evolving, with numerous local manufacturers entering the field, although foreign brands still dominate in terms of bidding numbers [15]. - Molecular Interaction Instruments: Currently, about 90% of the market is still occupied by foreign brands, but domestic companies are quickly developing and selling products, with many priced over one million [17]. Group 3: Future Outlook - The article concludes that the trend of domestic high-end life science instruments is not only a technological advancement but also a significant step towards enhancing research autonomy in China. The expectation is for more innovative companies to join this movement, pushing Chinese high-end scientific instruments from emerging to globally leading positions [21].