“以蚊治蚊”，5只绝育雄蚊对付1只野生雌蚊！

Core Viewpoint - Biological control technologies may become a significant aid for humanity in combating mosquito-borne infectious diseases, particularly in response to the recent outbreak of Chikungunya virus in southern China [3][12]. Group 1: Biological Control Methods - In response to the Chikungunya virus, Guangdong has implemented biological control methods, including "mosquito control by mosquitoes," to manage mosquito populations [3][4]. - The team from Sun Yat-sen University has cultivated non-biting giant mosquitoes to consume the larvae of Aedes albopictus, while Foshan has introduced fish species that feed on mosquito eggs and larvae in local water bodies [3][4]. Group 2: Mosquito Factory and Technology - Guangzhou Weibai Kun Biological Technology Co., known as the "mosquito factory," utilizes a method of releasing male mosquitoes infected with Wolbachia to mate with wild female mosquitoes, resulting in non-viable eggs [6][7]. - The factory has a production capacity of 5 million sterilized male mosquitoes per week, employing a release strategy of more than 5:1 to ensure effective mating with wild females [7]. - Monitoring data indicates that the introduction of sterilized male mosquitoes can stabilize mosquito populations within 5 to 10 minutes, with a potential reduction of mosquito numbers by 50% in three weeks and over 80% in six to eight weeks [7]. Group 3: Global Applications and Results - The Wolbachia technology has been successfully implemented in Brazil, where the release of Wolbachia-infected mosquitoes led to a 70% reduction in dengue cases and significant decreases in Chikungunya and Zika cases [10][11]. - The company has also collaborated with Mexico to establish a mosquito factory aimed at controlling dengue transmitted by Aedes aegypti, and Singapore's mosquito factory has achieved over 70% effectiveness in controlling dengue cases [11]. Group 4: Safety and Ethical Considerations - There are ongoing debates regarding the safety and stability of the "mosquito control by mosquitoes" technology, particularly concerning potential ecological impacts and the need for a robust legal and ethical framework [10]. - Concerns include the long-term stability of Wolbachia and the potential disruption of ecological balance, which could affect predators of mosquitoes and lead to the emergence of other mosquito species [10].