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Group 1 - The U.S. stock market experienced a decline, with the Dow Jones falling by 0.77% to 45,282.47 points, the S&P 500 down 0.43% to 6,439.32 points, and the Nasdaq decreasing by 0.22% to 21,449.29 points [2] - President Trump announced a drastic reduction in drug prices by 1400% to 1500%, which was perceived as a strong stance from the White House on drug pricing issues [6][10] - The Nasdaq Healthcare Index dropped by 1.85% following Trump's announcement, indicating a negative market reaction to the proposed drug price cuts [7] Group 2 - Several pharmaceutical stocks saw significant declines, with Moderna down 6.53%, and other major companies like Pfizer and Regeneron also experiencing drops of over 2% [10] - The cryptocurrency sector faced a collective downturn, with DeFi Development plummeting over 22%, and Bitcoin briefly falling below $110,000, marking a 3.3% drop within 24 hours [12][14] - The onshore Chinese yuan strengthened against the U.S. dollar, closing at 7.1517, an increase of 288 basis points from the previous trading day, influenced by dovish signals from the Federal Reserve [18]