张文宏：科技创新不能止于论文，须落地消除全球健康不平等

Core Viewpoint - The article emphasizes the importance of translating scientific research into practical applications to address global health disparities, particularly in low- and middle-income countries. The establishment of the Global Health Innovation Institute aims to facilitate this transition by focusing on the development of health products that meet the needs of these regions [3][4]. Group 1: Global Health Innovation Institute - The Global Health Innovation Institute is China's first research and development organization dedicated to global health, focusing on the transition of health products from the lab to the market [3][4]. - The initial five-year funding for the institute is jointly provided by the Shanghai government and the Gates Foundation, which includes project grants and technical support [4]. Group 2: Challenges in Disease Treatment - Significant challenges remain in combating infectious diseases such as tuberculosis and malaria, with China ranking third globally in new tuberculosis cases, reporting approximately 741,000 new cases in 2023 [6]. - The treatment of drug-resistant tuberculosis is particularly difficult and costly, with treatment durations typically exceeding 18-20 months and costs often surpassing 150,000 yuan [6]. Group 3: Research and Development Focus - The institute will concentrate on diseases like tuberculosis and malaria, as well as women's and children's health, aiming to provide technical support and resources to global partners [9]. - The Shanghai biopharmaceutical sector has developed a talent pool that includes public health experts and international cooperation specialists, which is crucial for the institute's mission [9]. Group 4: Successful Case Studies - The Levoplant contraceptive product, developed by Shanghai Dahua, has been recognized for its effectiveness and affordability, receiving pre-certification from the WHO in 2017 [9][10]. - A malaria control project initiated in collaboration with the Gates Foundation in Tanzania has shown positive results, leading to a decrease in malaria prevalence in the targeted areas [10].